General Info
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-PITX2 (1-100) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
Gene Symbol: | PITX2 |
Gene ID: | 5308 |
Uniprot ID: | PITX2_HUMAN |
Immunogen Region: | 1-100 |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Pituitary homeobox 2 (PITX2) (NP_000316.2). |
Immunogen Sequence: | MNCMKGPLHLEHRAAGTKLS AVSSSSCHHPQPLAMASVLA PGQPRSLDSSKHRLEVHTIS DTSSPEAAEKDKSQQGKNED VGAEDPSKKKRQRRQRTHFT |
Description
Post Translational Modifications | Phosphorylation at Thr-90 impairs its association with the CCND1 mRNA-stabilizing complex thus shortening the half-life of CCND1. |
Function | Controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, exerts a role in the expansion of muscle progenitors. May play a role in the proper localization of asymmetric organs such as the heart and stomach. Isoform PTX2C is involved in left-right asymmetry the developing embryo. |
Protein Name | Pituitary Homeobox 2All1-Responsive Protein Arp1Homeobox Protein Pitx2Paired-Like Homeodomain Transcription Factor 2Rieg Bicoid-Related Homeobox Transcription FactorSolurshin |
Database Links | Reactome: R-HSA-8866906 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Pituitary Homeobox 2 antibodyAnti-All1-Responsive Protein Arp1 antibodyAnti-Homeobox Protein Pitx2 antibodyAnti-Paired-Like Homeodomain Transcription Factor 2 antibodyAnti-Rieg Bicoid-Related Homeobox Transcription Factor antibodyAnti-Solurshin antibodyAnti-PITX2 antibodyAnti-ARP1 antibodyAnti-RGS antibodyAnti-RIEG antibodyAnti-RIEG1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance