| Short Description : | Mouse monoclonal anti-TGF-alpha for use in ELISA, FC, WB and IHC in Human, Rabbit and Zebrafish samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | ELISA/FC/WB/IHC |
| Host: | Mouse |
| Reactivity: | Human/Rabbit/Zebrafish |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | 1E8-G6 |
| Isotype: | IgMk |
| Conjugation: | Unconjugated |
| Concentration: | Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Purification: | Affinity purified from tissue culture. |
| Dilution Range: | ELISA (solid phase: not known; tracer: 0.001-100 µg/ml for 30 min at RT). Flow cytometry (0, 5-1, 0 Mu g/million cells in 0, 1ml). Immunoblotting (1-2 Mu g/ml). Immunohistology (1-2 µg/ml for 30 min at RT; staining of formalin-fixed tissues requires |
| Formulation: | PBS with 0.02% Sodium Azide. |
| Storage Instruction: | Store for up to 1 year at 2-8°C upon receipt. |
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| Immunogen: | A BALB/c mouse was immunized with synthetic TGF-alpha 34-43 decapeptide linked carrier. Fusion partner: Sp2/0-Ag14. |
| Tissue Specificity | Isoform 1, isoform 3 and isoform 4 are expressed in keratinocytes and tumor-derived cell lines. |
| Function | TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar. |
| Protein Name | Protransforming Growth Factor Alpha Cleaved Into - Transforming Growth Factor AlphaTgf-AlphaEgf-Like TgfEtgfTgf Type 1 |
| Database Links | |
| Cellular Localisation | Transforming Growth Factor Alpha: SecretedExtracellular SpaceProtransforming Growth Factor Alpha: Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Protransforming Growth Factor Alpha Cleaved Into - Transforming Growth Factor Alpha antibodyAnti-Tgf-Alpha antibodyAnti-Egf-Like Tgf antibodyAnti-Etgf antibodyAnti-Tgf Type 1 antibodyAnti-TGFA antibody |
Information sourced from Uniprot.org