General Info
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-TIE1 (350-600) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:200-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
Gene Symbol: | TIE1 |
Gene ID: | 7075 |
Uniprot ID: | TIE1_HUMAN |
Immunogen Region: | 350-600 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-600 of human TIE1 (NP_005415.1). |
Immunogen Sequence: | IPQILNMASELEFNLETMPR INCAAAGNPFPVRGSIELRK PDGTVLLSTKAIVEPEKTTA EFEVPRLVLADSGFWECRVS TSGGQDSRRFKVNVKVPPVP LAAPRLLTKQSRQLVVSPLV SFSGDGPISTVRLHYRPQDS TMDWSTIVVDPSENVTLMNL RPKTGYSVRVQLSRPGEGGE GAWGPPTLMTTDCPEPLLQP WLEGWHVEGTDRLRVSWSLP LVPGPLVGDGFLLRLWDGT |
Description
Tissue Specificity | Specifically expressed in developing vascular endothelial cells. |
Post Translational Modifications | Phosphorylated on tyrosine residues in response to ANGPT1, most likely by TEK/TIE2. |
Function | Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis. |
Protein Name | Tyrosine-Protein Kinase Receptor Tie-1 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Tyrosine-Protein Kinase Receptor Tie-1 antibodyAnti-TIE1 antibodyAnti-TIE antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance