BMS-561392 Formic acid

Référence T30531L-5mg

Conditionnement : 5mg

Marque : TargetMol


BMS-561392 Formic acid

(Synonyms: BMS-561392 Formic acid(611227-74-8 Free base)) Copy Product Info
BMS-561392 Formic acid (BMS-561392 formate) is a small molecule inhibitor, the formate salt form of BMS-561392. As a selective TACE inhibitor and ADAM17 blocker, this compound reduces TNFα levels and is primarily used for research on inflammation-related diseases such as inflammatory bowel disease.
BMS-561392 Formic acid
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:97.00%
ee:100%
Appearance:Solid
Color:White
COA LCMS CSFC ORP HNMR

Product Information

Bioactivity
Description
BMS-561392 Formic acid (BMS-561392 formate) is a small molecule inhibitor, the formate salt form of BMS-561392. As a selective TACE inhibitor and ADAM17 blocker, this compound reduces TNFα levels and is primarily used for research on inflammation-related diseases such as inflammatory bowel disease.
SynonymsBMS-561392 Formic acid(611227-74-8 Free base)
Chemical Properties
Molecular Weight522.59
FormulaC28H34N4O6
SmilesN[C@]1(C2=CC=C(C=C2)OCC3=CC(C)=NC4=C3C=CC=C4)C(N(CC1)[C@H](CC(C)C)C(NO)=O)=O.O=C(16)O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 250 mg/mL (478.39 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+90% Saline: 10 mg/mL (19.14 mM), Solution.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9135 mL9.5677 mL19.1355 mL95.6773 mL
5 mM0.3827 mL1.9135 mL3.8271 mL19.1355 mL
10 mM0.1914 mL0.9568 mL1.9135 mL9.5677 mL
20 mM0.0957 mL0.4784 mL0.9568 mL4.7839 mL
50 mM0.0383 mL0.1914 mL0.3827 mL1.9135 mL
100 mM0.0191 mL0.0957 mL0.1914 mL0.9568 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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