BRM/BRG1 ATP Inhibitor-1 [2270879-17-7]
Référence T10616-1mg
Conditionnement : 1mg
Marque : TargetMol
BRM/BRG1 ATP Inhibitor-1
BRM/BRG1 ATP Inhibitor-1
Select Batch
Purity:99.84%
COA LCMS HNMR
Product Introduction
Bioactivity
Chemical Properties
| Description | BRM/BRG1 ATP Inhibitor-1 is an allosteric dual Brahma homolog (BRM)/SWI/SNF related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2) and BRG1/SMARCA4 ATPase activity inhibitor (IC50s<0.005 μM). |
| Targets&IC50 | BRM/BRG1:﹤0.005 µM |
| Molecular Weight | 318.27 |
| Formula | C11H9F3N4O2S |
| Cas No. | 2270879-17-7 |
| Smiles | OCc1cnc(F)cc1NC(=O)Nc1cc(ns1)C(F)F |
| Relative Density. | 1.659 g/cm3 (Predicted) |
| Color | White |
| Appearance | Solid |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 250 mg/mL (785.5 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (15.71 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||