QC Test

Hybridization position of the probes on the chromosome.

Hybridization position of the probes on the chromosome.

Hybridization position of the probes on the chromosome.

  • Specification

    Product Description

    Labeled FISH probes for identification of gene split using Fluorescent In Situ Hybridization Technique. (Technology).

    Probe 1

    Name: CCND2
    Size: Approximately 580kb
    Fluorophore: Texas Red
    Location: 12p13.32

    Probe 2

    Name: CCND2
    Size: Approximately 690kb
    Fluorophore: FITC
    Location: 12p13.32

    Probe Gap

    The gap between two probes is approximately 90 kb




    Genomic DNA






    We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.

    Regulation Status

    For research use only (RUO)

    Quality Control Testing

    Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

    Supplied Product

    DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe

    Storage Instruction

    Store at 4°C in the dark.


    Hybridization position of the probes on the chromosome.

  • Applications

    Fluorescent In Situ Hybridization (Cell)

  • Gene Info — CCND2

    Entrez GeneID


    Gene Name


    Gene Alias

    KIAK0002, MGC102758

    Gene Description

    cyclin D2

    Omim ID


    Gene Ontology


    Gene Summary

    The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. [provided by RefSeq

    Other Designations

    G1/S-specific cyclin D2

  • Interactome
  • Pathway
  • Disease
  • Publication Reference