CD56 (Neural Cell Adhesion Molecule, NCAM) (AP)
Référence MBS6122177-0,1mL
Conditionnement : 0.1mL
Marque : MyBiosource
CD56 (Neural Cell Adhesion Molecule, NCAM) (AP)
CD56 Antibody – Mouse Monoclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6122177MBS6122177 is an antibody targeting CD56. Also known as CD56 (Neural Cell Adhesion Molecule, NCAM) (AP). Reactive in Human, Rat, Zebrafish. Host: Mouse. More details
Product Overview
Online Datasheet in PDFProduct Name
CD56, Monoclonal Antibody
Full Product Name
CD56 (Neural Cell Adhesion Molecule, NCAM) (AP)
Product Gene Name
anti-CD56 antibody
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
123C3.D5
Host
Mouse
Species Reactivity
Human, Rat, Zebrafish
Form/Format
Supplied as a liquid in 10mM PBS. No preservative added. BSA-Free. Labeled with Alkaline Phosphatase (AP).
Purity/Purification
Purified by Protein G Affinity Chromatography
Specificity
Recognizes human CD56. Species Crossreactivity: rat and zebrafish. Recognizes two proteins (185kD & 145kD), identified as two isoforms of neural cell adhesion molecule (NCAM/CD56).
Preparation and Storage
May be stored at 4 degree C before opening. DO NOT FREEZE! Stable at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing alkaline phosphatase conjugates will result in a substantial loss of activity.
Applications Tested/Suitable for anti-CD56 antibody
ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-CD56 antibody
IP: 1-2ug/500ug protein lysate
IF: 1-2ug/ml
WB: 0.5-1ug/ml
Applications are based on unconjugated antibody.
IF: 1-2ug/ml
WB: 0.5-1ug/ml
Applications are based on unconjugated antibody.
Product References and Citations for anti-CD56 antibody
1. Gerardy-Schahn R; et. al. Int Journal of Cancer. Supplement, 1994, 8:38-42. 2. Michalides R; et. al. International Journal of Cancer. Supplement, 1994, 8:34-7. 3. Schol DJ; et. al. Int J Cancer. Supplement, 1988, 2:34-40.
Other Notes
Small volumes of anti-CD56 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for CD56. It may not necessarily be applicable to this product.
NCBI Official Full Name
neural cell adhesion molecule 1 isoform 1
NCBI Official Synonym Full Names
neural cell adhesion molecule 1
NCBI Official Symbol
NCAM1
NCBI Official Synonym Symbols
CD56; NCAM; MSK39
UniProt Protein Name
Neural cell adhesion molecule 1
UniProt Synonym Protein Names
CD_antigen: CD56
UniProt Gene Name
NCAM1
UniProt Synonym Gene Names
NCAM; N-CAM-1; NCAM-1
UniProt Entry Name
NCAM1_HUMAN
NCBI Protein Information
neural cell adhesion molecule 1; antigen recognized by monoclonal antibody 5.1H11; neural cell adhesion molecule, NCAM
UniProt Comments for CD56
NCAM1: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, GPI anchor; Membrane protein, integral; Cell adhesion; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 11q23.1
Cellular Component: Golgi membrane; cell surface; membrane; integral to membrane; plasma membrane; external side of plasma membrane
Molecular Function: identical protein binding
Biological Process: axon guidance; extracellular matrix organization and biogenesis; cytokine and chemokine mediated signaling pathway; cell adhesion
Show more Protein type: Membrane protein, GPI anchor; Membrane protein, integral; Cell adhesion; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 11q23.1
Cellular Component: Golgi membrane; cell surface; membrane; integral to membrane; plasma membrane; external side of plasma membrane
Molecular Function: identical protein binding
Biological Process: axon guidance; extracellular matrix organization and biogenesis; cytokine and chemokine mediated signaling pathway; cell adhesion
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with anti-CD56 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Axon Guidance Pathway antibodies | Axon Guidance Pathway Diagram |
| BDNF Signaling Pathway antibodies | BDNF Signaling Pathway Diagram |
| Cardiac Progenitor Differentiation Pathway antibodies | Cardiac Progenitor Differentiation Pathway Diagram |
| Cell Adhesion Molecules (CAMs) Pathway antibodies | Cell Adhesion Molecules (CAMs) Pathway Diagram |
| Cell Adhesion Molecules (CAMs) Pathway antibodies | Cell Adhesion Molecules (CAMs) Pathway Diagram |
| Cytokine Signaling In Immune System Pathway antibodies | Cytokine Signaling In Immune System Pathway Diagram |
| Developmental Biology Pathway antibodies | Developmental Biology Pathway Diagram |
| ECM Proteoglycans Pathway antibodies | ECM Proteoglycans Pathway Diagram |
| Extracellular Matrix Organization Pathway antibodies | Extracellular Matrix Organization Pathway Diagram |
| FGF Signaling Pathway antibodies | FGF Signaling Pathway Diagram |
Diseases associated with anti-CD56 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Nervous System Diseases Antibodies | >984 publications with CD56 and Nervous System Diseases |
| Brain Diseases Antibodies | >537 publications with CD56 and Brain Diseases |
| Necrosis Antibodies | >276 publications with CD56 and Necrosis |
| Disease Models, Animal Antibodies | >257 publications with CD56 and Disease Models, Animal |
| Inflammation Antibodies | >237 publications with CD56 and Inflammation |
| Lung Neoplasms Antibodies | >224 publications with CD56 and Lung Neoplasms |
| Cardiovascular Diseases Antibodies | >219 publications with CD56 and Cardiovascular Diseases |
| Congenital Abnormalities Antibodies | >195 publications with CD56 and Congenital Abnormalities |
| Liver Diseases Antibodies | >179 publications with CD56 and Liver Diseases |
| Neoplasm Invasiveness Antibodies | >146 publications with CD56 and Neoplasm Invasiveness |
Organs/Tissues associated with anti-CD56 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >2715 publications with CD56 and Brain |
| Blood Antibodies | >2492 publications with CD56 and Blood |
| Nerve Antibodies | >1729 publications with CD56 and Nerve |
| Embryonic Tissue Antibodies | >831 publications with CD56 and Embryonic Tissue |
| Muscle Antibodies | >564 publications with CD56 and Muscle |
| Bone Antibodies | >525 publications with CD56 and Bone |
| Skin Antibodies | >379 publications with CD56 and Skin |
| Vascular Antibodies | >365 publications with CD56 and Vascular |
| Eye Antibodies | >337 publications with CD56 and Eye |
| Lung Antibodies | >326 publications with CD56 and Lung |


