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> Cd68 Mouse Monoclonal Antibody [Clone ID: ED1]

Cd68 Mouse Monoclonal Antibody [Clone ID: ED1]

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Référence BM4000B

Conditionnement : 100Tests


Cd68 Mouse Monoclonal Antibody [Clone ID: ED1]

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SKU
BM4000B
Cd68 mouse monoclonal antibody, clone ED1, Biotin
Size:
100 Tests
Conjugation:
Biotin Unconjugated FITC
 

View other "Cd68 or NP_001026808.1" antibodies

Specifications
Product Data
Clone Name ED1
Application FC, IHC
Recommended Dilution Flow Cytometry: Use 10 µl of neat antibody to label 10e6 cells in 100 µl.
(Results maybe enhanced using membrane permeabilisation).
Immunohistochemistry on Frozen sections: 1/10.
Reactivity Bovine, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Rat spleen cells
Specificity CD68 antibody (Cat.-No BM4000B) recognizes a single chain glycoprotein of 110kDa that is expressed predominantly on the lysomal membrane of myeloid cells. Weak cell surface expression also occurs. The antigen is expressed by the majority of tissue macrophages, and weakly be peripheral blood granulocytes. Studies have shown that the antigen recognised by ED1 is the rat homologue of Human CD68.
Negative Species: Horse.
Buffer PBS, pH 7.2
Label: Biotin
State: Liquid purified IgG fraction
Stabilizer: 1% BSA
Preservative: 0.09% Sodium Azide
Concentration lot specific
Purification Affinity Chromatography on Protein A
Conjugation Biotin
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name Cd68 molecule
Database Link
Background The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells.
Synonyms Gp110, Macrosialin, Macrophage marker
Reference Data
Product Manuals
FAQs
  • Antibody and Western Standard
SDS

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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