A8655-25mg | Ciliobrevin A [302803-72-1] Clinisciences

Background

Hedgehog (Hh) pathway antagonist; blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC50 = 7 μM) downstream of Smo. Peturbs primary cilia formation; inhibits cytoplasmic AAA+ ATPase dynein-dependent microtubule gliding and ATPase activity.

Chemical Properties

Physical Appearance	Yellow solid
Storage	Store at -20°C
M.Wt	358.18
Cas No.	302803-72-1
Formula	C₁₇H₉Cl₂N₃O₂
Solubility	Soluble in DMSO
Chemical Name	(2E)-3-(2,4-dichlorophenyl)-3-oxo-2-(4-oxo-1H-quinazolin-2-ylidene)propanenitrile
SDF	Download SDF
Canonical SMILES	C1=CC=C2C(=C1)C(=O)NC(=C(C#N)C(=O)C3=C(C=C(C=C3)Cl)Cl)N2
Shipping Condition	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips	We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Purity = 98.00%

COA (Certificate Of Analysis)
MSDS (Material Safety Data Sheet)
Datasheet

Chemical structure

Ciliobrevin A [302803-72-1]

Référence A8655-25mg

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Background

Chemical Properties

Quality Control

Chemical structure