A2578-100ug | Clasto-Lactacystin β-lactone [154226-60-5] Clinisciences

Background

Cell-permeable. A highly specific, potent and irreversible proteasome inhibitor. Lactacystin (Cat. No. 1709-200) acts as a precursor for clasto-lactacystin β-lactone and the latter compound is at least 10 times more active than the parent Lactacystin

Product Citation

2. Zhijun Liu, Himani Nailwal, et al. "A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation." Immunity. 2021 Feb 9;54(2):247-258.e7. PMID: 33444549

Chemical Properties

Physical Appearance	A solution in methyl acetate
Storage	Store at -20°C
M.Wt	213.23
Cas No.	154226-60-5
Formula	C₁₀H₁₅NO₄
Solubility	Soluble in DMSO
Chemical Name	(1R,2S,5S)-5-[(1R)-1-hydroxy-2-methylpropyl]-2-methyl-7-oxa-4-azabicyclo[3.2.0]heptane-3,6-dione
SDF	Download SDF
Canonical SMILES	CC1C2C(C(=O)O2)(NC1=O)C(C(C)C)O
Shipping Condition	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips	We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Purity ≥95.00%

COA (Certificate Of Analysis)
MSDS (Material Safety Data Sheet)

Chemical structure

Clasto-Lactacystin β-lactone [154226-60-5]

Référence A2578-100ug

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