Dectin 1 (CLEC7A) (NM_022570) Human Tagged ORF Clone Lentiviral Particle

Specifications

Product Data
Type	Human Tagged ORF Clone Lentiviral Particle
Tag	Myc-DDK
Symbol	CLEC7A
Synonyms	BGR; CANDF4; CD369; CLECSF12; DECTIN1; SCARE2
Mammalian Cell Selection	Puromycin
Vector	pLenti-C-Myc-DDK-P2A-Puro
ACCN	NM_022570
ORF Size	603 bp
Sequence Data	ORF Nucleotide Sequence (showhide) The ORF insert of this clone is exactly the same as(RC221791).
OTI Disclaimer	Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at info@clinisciences.com The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation	This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq	NM_022570.4
RefSeq Size	2484 bp
RefSeq ORF	606 bp
Locus ID	64581
UniProt ID	Q9BXN2
Cytogenetics	12p13.2
Domains	CLECT
Protein Families	Druggable Genome, Transmembrane
MW	22.6 kDa
Gene Summary	This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]