EpoY [245660-13-3]

Référence NB-64-101064-25mg

Conditionnement : 25mg

Marque : Neo Biotech


EpoY (Synonyms: SD-142)

Catalog No. T201297 Copy Product Info
EpoY (SD-142) is an irreversible inhibitor of the primary brain microtubule-associated tyrosine carboxypeptidase (TCP), a complex formed by vasohibin-1 (VASH1) and small vasohibin-binding protein (SVBP). By inhibiting TCP with an IC50 value of approximately 500 nM, EpoY effectively reduces the levels of detyrosinated α-tubulin, which is crucial for microtubule dynamics and neuronal differentiation. This inhibition results in significant differentiation defects and is linked to potential issues related to cancer and cardiomyopathy.

EpoY

Copy Product Info
Synonyms SD-142

EpoY (SD-142) is an irreversible inhibitor of the primary brain microtubule-associated tyrosine carboxypeptidase (TCP), a complex formed by vasohibin-1 (VASH1) and small vasohibin-binding protein (SVBP). By inhibiting TCP with an IC50 value of approximately 500 nM, EpoY effectively reduces the levels of detyrosinated α-tubulin, which is crucial for microtubule dynamics and neuronal differentiation. This inhibition results in significant differentiation defects and is linked to potential issues related to cancer and cardiomyopathy.

EpoY
Cas No. 245660-13-3

Product Introduction

Bioactivity
Description
EpoY (SD-142) is an irreversible inhibitor of the primary brain microtubule-associated tyrosine carboxypeptidase (TCP), a complex formed by vasohibin-1 (VASH1) and small vasohibin-binding protein (SVBP). By inhibiting TCP with an IC50 value of approximately 500 nM, EpoY effectively reduces the levels of detyrosinated α-tubulin, which is crucial for microtubule dynamics and neuronal differentiation. This inhibition results in significant differentiation defects and is linked to potential issues related to cancer and cardiomyopathy.
SynonymsSD-142
Chemical Properties
Molecular Weight323.30
FormulaC15H17NO7
Cas No.245660-13-3
SmilesC(N[C@@H](CC1=CC=C(O)C=C1)C(O)=O)(=O)[C@@H]2[C@@H](C(OCC)=O)O2
Storage & Solubility Information
StorageShipping with blue ice/Shipping at ambient temperature.