Human Acyl coenzyme A Thioesterase 4 (ACOT4) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ACOT4
Locus ID	122970
Kit Components	GA114795G1, Acyl coenzyme A Thioesterase 4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114795G2, Acyl coenzyme A Thioesterase 4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114795G3, Acyl coenzyme A Thioesterase 4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_152331
UniProt ID	Q8N9L9
Synonyms	PTE-Ib; PTE1B; PTE2B
Summary	Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (PubMed:16940157). ACOT4 is a peroxisomal succinyl-coenzyme A thioesterase can also hydrolyze glutaryl-CoA and long chain saturated acyl-CoAs (PubMed:16940157).[UniProtKB/Swiss-Prot Function]