Human Chorionic Gonadotropin

Référence MBS142644-5mg

Conditionnement : 5mg

Marque : MyBiosource


Chorionic Gonadotropin (hCG) Human Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS142644

Description: Human Chorionic Gonadotropin is produced from a sterile preparation of placental glucoprotein urine of pregnant women having a total molecular mass of 36,700 Dalton. The hCG consists of 237 amino acids, a chain-92 amino acids and b chain-145… More details

Product Overview

Online Datasheet in PDF
Product Name
Chorionic Gonadotropin (hCG), Active Protein
Full Product Name
Human Chorionic Gonadotropin
Product Gene Name
hCG active protein
Product Synonym Names
hCG; Chorionic Gonadotropin Human; Chorionic gonadotropin; hCG; CG
Host
Urine of pregnant women
Form/Format
The hCG was lyophilized with no additives.
Preparation and Storage
Lyophilized hCG although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CG-beta should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
OMIM
118860
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Physical Apperance
Sterile Filtered White Lyophilized (freeze-dried) powder.
Solubility
It is recommended to reconstitute the lyophilized Human Chorionic Gonadotropin in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity
The activity was found to be 5188IU/mg.
Contaminants
Free of: HbsAg and antibodies to HIV and HCV.

Product Categories/Family for hCG active protein

Hormones; Hormones; HCG

Other Notes

Small volumes of hCG active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for hCG purchase

MBS142644 is an active protein targeting hCG. Also known as Human Chorionic Gonadotropin. Host: Urine of pregnant women.

Additional Details

NCBI/Uniprot data below describe general gene information for hCG. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
choriogonadotropin subunit beta
NCBI Official Synonym Full Names
chorionic gonadotropin, beta polypeptide
NCBI Official Symbol
CGB
NCBI Official Synonym Symbols
CGB3; CGB5; CGB7; CGB8; hCGB
UniProt Protein Name
Choriogonadotropin subunit beta
UniProt Synonym Protein Names
Chorionic gonadotrophin chain beta
Protein Family
Hemocyanin
UniProt Gene Name
CGB
UniProt Synonym Gene Names
CGB3; CG-beta
UniProt Entry Name
CGHB_HUMAN
NCBI Protein Information
choriogonadotropin subunit beta; CG-beta; chorionic gonadotrophin chain beta; chorionic gonadotropin beta 3 subunit; chorionic gonadotropin beta chain; chorionic gonadotropin beta subunit

NCBI Summary for hCG

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for hCG

CGB: Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. Belongs to the glycoprotein hormones subunit beta family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Inhibitor; Secreted

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: extracellular region

Molecular Function: hormone activity

Biological Process: cellular protein metabolic process; cell-cell signaling; apoptosis; peptide hormone processing; female gamete generation; signal transduction
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with hCG active protein

 Products by Pathway  Pathway Diagram
 Glycoprotein Hormones Pathway antibodies  Glycoprotein Hormones Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Peptide Hormone Biosynthesis Pathway antibodies  Peptide Hormone Biosynthesis Pathway Diagram
 Peptide Hormone Metabolism Pathway antibodies  Peptide Hormone Metabolism Pathway Diagram

Diseases associated with hCG active protein

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >20 publications with hCG and Breast Neoplasms
 Cardiovascular Diseases Antibodies  >8 publications with hCG and Cardiovascular Diseases
 Congenital Abnormalities Antibodies  >5 publications with hCG and Congenital Abnormalities
 Pain Antibodies  >5 publications with hCG and Pain
 Fibrosis Antibodies  >5 publications with hCG and Fibrosis
 Inflammation Antibodies  >5 publications with hCG and Inflammation
 Neoplasm Invasiveness Antibodies  >4 publications with hCG and Neoplasm Invasiveness
 Hypertension Antibodies  >4 publications with hCG and Hypertension
 Neoplasms, Experimental Antibodies  >4 publications with hCG and Neoplasms, Experimental
 Hyperplasia Antibodies  >4 publications with hCG and Hyperplasia

Organs/Tissues associated with hCG active protein

 Organ/Tissue Name  Pubmed Publications
 Placenta Antibodies  >25 publications with hCG and Placenta
 Embryonic Tissue Antibodies  >13 publications with hCG and Embryonic Tissue
 Heart Antibodies  >8 publications with hCG and Heart
 Testis Antibodies  >6 publications with hCG and Testis
 Skin Antibodies  >4 publications with hCG and Skin