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Sandwich ELISA
Application

Sandwich ELISA

Detection limit for HbA1c is approximately 1ng/ml as a capture antibody.

  • Specification

    Product Description

    Mouse monoclonal antibody raised against glycosylated hemoglobin.

    Immunogen

    A peptide (conjugated with KLH) corresponding to N-terminus glycosylated HbA1c.

    Host

    Mouse

    Reactivity

    Human

    Form

    Liquid

    Conjugation

    KLH

    Isotype

    IgG2b, kappa

    Recommend Usage

    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.4

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Sandwich ELISA

    Detection limit for HbA1c is approximately 1ng/ml as a capture antibody.
  • Gene Info — HBA1

    Entrez GeneID

    3039

    GeneBank Accession#

    NM_000558

    Protein Accession#

    NP_000549

    Gene Name

    HBA1

    Gene Alias

    HBH, HBA-T3

    Gene Description

    hemoglobin, alpha 1

    Omim ID

    141800

    Gene Ontology

    Hyperlink

    Gene Summary

    The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. [provided by RefSeq

    Other Designations

    alpha 1 globin|alpha one globin|alpha-1 globin|alpha-1-globin|hemoglobin alpha 1 globin chain|hemoglobin alpha-1 chain

  • Interactome
  • Disease