Human PKDREJ activation kit by CRISPRa

CAT#: GA107049

PKDREJ CRISPRa kit - CRISPR gene activation of human polycystin family receptor for egg jelly



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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol PKDREJ
Locus ID 10343
Kit Components

GA107049G1, PKDREJ gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107049G2, PKDREJ gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107049G3, PKDREJ gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_006071
UniProt ID Q9NTG1
Synonyms OTTHUMP00000028714; polycystic kidney disease (polycystin) and REJ (sperm receptor for egg jelly, sea urchin homolog)-like; polycystic kidney disease (polycystin) and REJ (sperm receptor for egg jelly homolog, sea urchin)-like; receptor for egg jelly-like
Summary This intronless gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a receptor for egg jelly (REJ) domain, a G-protein-coupled receptor proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may play a role in human reproduction. Alternative splice variants have been described but their biological natures have not been determined. [provided by RefSeq, Jul 2008]

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