Human WNT1 (Wingless Type MMTV Integration Site Family, Member 1) Sandwich ELISA Kit Ready-To-Use E0019482)

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	WNT1
Gene ID:	7471
Uniprot ID:	WNT1_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity
Post Translational Modifications	Palmitoleoylation is required for efficient binding to frizzled receptors. Palmitoleoylation is necessary for proper trafficking to cell surface (Probable). Depalmitoleoylated by NOTUM, leading to inhibit Wnt signaling pathway.
Function	Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Plays an essential role in the development of the embryonic brain and central nervous system (CNS). Has a role in osteoblast function, bone development and bone homeostasis.
Protein Name	Proto-Oncogene Wnt-1 Proto-Oncogene Int-1 Homolog
Database Links	Reactome: R-HSA-201681 Reactome: R-HSA-3238698 Reactome: R-HSA-373080 Reactome: R-HSA-381340 Reactome: R-HSA-4086400 Reactome: R-HSA-4641262
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix
Alternative ELISA Names	Proto-Oncogene Wnt-1 ELISA kit Proto-Oncogene Int-1 Homolog ELISA kit WNT1 ELISA kit INT1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance