Integrin alpha V beta 3 Protein, Human, Recombinant (His)
Référence NB-64-60604-500ug
Conditionnement : 500ug
Marque : Neo Biotech
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Integrin alpha V beta 3 Protein, Human, Recombinant (His)
(Synonyms: Integrin α V β 3, Integrin alpha V β3) Copy Product InfoSynonyms: Integrin α V β 3, Integrin alpha V β3
Catalog No. TMPY-05716 Copy Product Info
Integrin alpha-V & beta-3 (ITGAV/ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:SDS-PAGE: 94.9%; SEC-HPLC: 91.6%
Appearance:Lyophilized powder
Color:White
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Product Information
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Integrin alpha-V & beta-3 (ITGAV/ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | P06756&P05106 |
| Construction | A DNA sequence encoding the extracellular domain (Met1-Val992) of human ITGAV (P06756) was fused with a his tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the extracellular domain (Met1-Asp718) of human ITGB3 (P05106) constructed the plasmid 2. The two plasmids were co-expressed and the human ITGAV&ITGB3 heterodimer was purified. Predicted N terminal: Phe31 & Gly27 |
| Protein Purity | ≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC. |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot. |
| Synonyms | Integrin α V β 3, Integrin alpha V β3 |
| Research Background | Integrin alpha-V & beta-3 (ITGAV/ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. |
| Molecular Weight | 193.32 kDa (predicted) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: Integrin alpha V beta 3 Protein, Human, Recombinant (His) chemical structure | Integrin alpha V beta 3 Protein, Human, Recombinant (His) molecular weight
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