ITGA4 Antibody
Référence OABF00236
Conditionnement : 100ul
Marque : Aviva Systems Biology
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Téléphone : +1 850 650 7790
| Datasheets/Manuals | Printable datasheet for ITGA4 Antibody (OABF00236) |
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| Predicted Species Reactivity | Bovine|Horse|Human|Mouse|Rabbit|Rat |
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| Product Format | Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | ELISA, IA |
| Additional Information | Subcellular location: Extracellular |
| Reconstitution and Storage | -20°C |
| Immunogen | KLH conjugated synthetic peptide derived from human Integrin alpha 4 |
| Purification | Protein A Purified |
| Concentration | 1 ug/ul |
| Application Info | WB: 1:100 - 1000 FC: 1:20 - 100 IHC-P: : 1:100 - 500 |
| Gene Symbol | ITGA4 |
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| Gene Full Name | integrin subunit alpha 4 |
| Alias Symbols | 269C wild type;alpha 4 subunit of VLA-4 receptor;antigen CD49D, alpha-4 subunit of VLA-4 receptor;CD49 antigen-like family member D;CD49D;IA4;integrin alpha-4;integrin alpha-IV;very late activation protein 4 receptor, alpha 4 subunit;VLA-4 subunit alpha. |
| NCBI Gene Id | 3676 |
| Protein Name | Integrin alpha-4 |
| Description of Target | Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells. ITGA4:ITGB1 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (PubMed:23125415). ITGA4:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:18635536, PubMed:25398877). |
| Uniprot ID | P13612 |
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What is the species homology for "ITGA4 Antibody (OABF00236)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Bovine|Horse|Human|Mouse|Rabbit|Rat".
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How long will it take to receive "ITGA4 Antibody (OABF00236)"?
This item is available "3 to 5 business days.".
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What buffer format is "ITGA4 Antibody (OABF00236)" provided in?
This item is provided in "Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "ITGA4 Antibody (OABF00236)"?
This target may also be called "269C wild type;alpha 4 subunit of VLA-4 receptor;antigen CD49D, alpha-4 subunit of VLA-4 receptor;CD49 antigen-like family member D;CD49D;IA4;integrin alpha-4;integrin alpha-IV;very late activation protein 4 receptor, alpha 4 subunit;VLA-4 subunit alpha." in publications.
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What is the shipping cost for "ITGA4 Antibody (OABF00236)"?
The shipping cost for this item is within the US. Please contact us for specific shipping for international orders.
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What is the guarantee for "ITGA4 Antibody (OABF00236)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "ITGA4 Antibody (OABF00236)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "ITGA4 Antibody (OABF00236)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ITGA4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ITGA4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ITGA4"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ITGA4"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ITGA4"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ITGA4"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.