Clinisciences > Lewis X tetrasaccharide [23425-36-7]
Lewis X tetrasaccharide [23425-36-7]
Référence OL09569-10mg
Conditionnement : 10mg
Marque : Biosynth
CAS No
[23425-36-7]
Synonyms
Gal-b-1-4(Fuc-a-1-3)GlcNAc-b-1-3-Gal
Product Code
OL09569
MDL No
MFCD15145462
MOL file
Chemical Formula
C26H45NO20
Molecular Weight
691.64 g/mol
Smiles
O([C@H]1[C@H](O[C@H]2[C@@H](O)[C@H](O)[C@H](O)[C@H](C)O2)[C@@H](O)[C@H](O[C@@H]([C@H]([C@@H](CO)O)O)[C@H](C=O)O)O[C@@H]1CO)[C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O
Long Term Storage
store at <-15°C
Storage
store at <-15°C
Precautionary Statement Code
P261, P262
Harmonized Tariff Codes
Switzerland: 29400000 - USA: 2940006000 - Slovakia: 2940000080 - UK: 2940000000 - China: 2940009000
Lewis X tetrasaccharide (LX4) is a glycan that is found on the surface of human cells. It is an important diagnostic marker for microbial infections and has been shown to be present on the surfaces of both normal skin cells and malignant cells. The presence of LX4 can be detected using a monoclonal antibody in vitro. This glycan can also be used as a model system to study ischemia–reperfusion injury, since it has been shown to be sensitive to oxidative changes caused by reactive oxygen species generated during reperfusion. Studies have also shown that LX4 binds to enzymes such as malonic acid oxydoreductase, which are involved in the metabolism of lysine, arginine, and proline.