Maltodextrin, dextrose equivalent 5.0-8.0 [9050-36-6]

Commande minimum 2

Référence HY-W250795B-25g

Conditionnement : 25g

Marque : MedChemExpress


Description

Maltodextrin, dextrose equivalent 5.0-8.0 can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

In Vitro

Maltodextrin, dextrose equivalent 5.0-8.0 is a polysaccharide with good biocompatibility and drug encapsulation ability, that encapsulates BSA as a model protein with an efficiency of about 70% and a loading rate of up to 20%. Maltodextrin, dextrose equivalent 5.0-8.0 exhibits non-toxic to cells at a concentrations of 5 mg/mL, and can be used in drug delivery system. The glucose equivalent (DE) value reflects the degree of hydrolysis of maltodextrin. The higher the DE value, the higher the degree of hydrolysis is. Maltodextrin, dextrose equivalent 5.0-8.0 forms stable nanoparticles with particle sizes ranging from 170 nm to 450 nm and a narrow particle size distribution[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Formule

(C6H10O5)n·xH2O

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O[C@@H]2[C@@H](COC)O[C@H](O08)[C@H](O)[C@H]2O)O1.26.[x]

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Store at room temperature, keep dry and cool

In solvent -80°C 1 year
-20°C 6 months
Solvant et solubilité
In Vitro: 

DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

  • Calculateur de molarité

  • Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureté et documentation
Références