Melphalan [148-82-3]
Référence NB-64-110138-5mg
Conditionnement : 5mg
Marque : Neo Biotech
Melphalan (Synonyms: L-PAM)
Catalog No. T60710 Copy Product Info
Melphalan is an orally bioavailable DNA alkylating agent exhibiting antitumour activity, commonly employed in cancer chemotherapy.
Melphalan
Copy Product InfoSynonyms L-PAM
Melphalan is an orally bioavailable DNA alkylating agent exhibiting antitumour activity, commonly employed in cancer chemotherapy.
Cas No. 148-82-3
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Melphalan is an orally bioavailable DNA alkylating agent exhibiting antitumour activity, commonly employed in cancer chemotherapy. |
| In vivo | In SD rats, high-temperature treatment affects the pharmacokinetics of intraperitoneally administered Melphalan (12 mg/kg): it reduces the area under the curve (AUC) of melphalan in the peritoneal fluid and does not increase the AUC of melphalan in plasma. Meanwhile, high-temperature treatment can elevate the concentration of melphalan in intraperitoneal tissues. |
| Synonyms | L-PAM |
| Molecular Weight | 305.21 |
| Formula | C13H18Cl2N2O2 |
| Cas No. | 148-82-3 |
| Smiles | N(CCCl)(CCCl)C1=CC=C(C[C@@H](C(O)=O)N)C=C1 |
| Storage | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||
| Solubility Information | H2O: 3.1 mg/mL (10.16 mM), when pH is adjusted to 2 with HCl. DMSO: 4 mg/mL (13.11 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
H2O/DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | |||||||||||||||||||||
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