Mouse Monoclonal Anti-Adeno-associated virus (AAV), VP1, VP2, VP3 (Clone A69)
Référence 03-65157-1ml
Conditionnement : 1ml
Marque : American Research Products
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Anti-Adeno-associated virus (AAV), VP1, VP2, VP3
| Product Name | Anti-Adeno-associated virus (AAV), VP1, VP2, VP3 |
|---|---|
| Description | Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease and consequently the virus causes a very mild immune response. Gene therapy vectors using AAV can infect both dividing and quiescent cells and persist in an extrachromosomal state without integrating into the genome of the host cell. These features make AAV a very attractive candidate for creating viral vectors for gene therapy, and for the creation of isogenic human disease models. Mouse Monoclonal Antibody to Adeno-associated virus (AAV), VP 1 & VP2. A69 reacts with VP 1 and VP 2 of adeno-associated virus which are highly enriched in the nucleus. |
| Synonyms | AAV2 |
| Clone | A69 |
| Immunogen | Adeno-associated virus capsid proteins and virus particles |
| Isotype | IgG1 |
| Specificity | Epitope mapping experiments (Wobus et al.) identified aa 169 to aa 184 of VP2 and (with reduced intensity) aa 123 to aa136 of VP1 capsid proteins as the specific binding region. |
| Reactivity | Human, Primate |
| Applications | IF, IHC, IP, WB |
| Form | Hybridoma culture supernatant |
| Storage | 2-8C |
| References | Wistuba, A. et al. (1995) J. Virol. 69: 5311-5319Wistuba, A. et al. (1997) J. Virol. 71: 1341-1352Wobus,CE. et al. (2000) J. Virol 74 (19): 9281-9292 |
| Supplier | ARP |
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