- Specifications
Product Description
Made to order FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. ().
Origin
Human
Source
Genomic DNA
Reactivity
Human
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Supplied Products
DAPI Counterstain (1500 ng/mL ) 250 uL
Storage Instruction
Store at 4°C in the dark.
- Applications
Fluorescent In Situ Hybridization (Cell)
- Gene Info — NBN
Entrez GeneID
4683Gene Name
NBN
Gene Alias
AT-V1, AT-V2, ATV, FLJ10155, MGC87362, NBS, NBS1, P95
Gene Description
nibrin
Gene Ontology
HyperlinkGene Summary
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq
Other Designations
Nijmegen breakage syndrome 1 (nibrin)|cell cycle regulatory protein p95|p95 protein of the MRE11/RAD50 complex
- Interactomes
- Pathways
- Diseases
NBN FISH Probe
Référence FA0222
Conditionnement : 200uL