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Western Blot detection against Immunogen (37.84 KDa) .

  • Specification

    Product Description

    Mouse monoclonal antibody raised against a partial recombinant PLAUR.

    Immunogen

    PLAUR (NP_002650, 25 a.a. ~ 134 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    Sequence

    CMQCKTNGDCRVEECALGQDLCRTTIVRLWEEGEEPELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGNSGRAVTYSRSRYLECISCGSSDMSCERGRHQS

    Host

    Mouse

    Reactivity

    Human

    Interspecies Antigen Sequence

    Mouse (60); Rat (60)

    Isotype

    IgG1 Kappa

    Quality Control Testing

    Antibody Reactive Against Recombinant Protein.

    Western Blot detection against Immunogen (37.84 KDa) .

    Storage Buffer

    In 1x PBS, pH 7.4

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot (Recombinant protein)

    ELISA

  • Gene Info — PLAUR

    Entrez GeneID

    5329

    GeneBank Accession#

    NM_002659

    Protein Accession#

    NP_002650

    Gene Name

    PLAUR

    Gene Alias

    CD87, UPAR, URKR

    Gene Description

    plasminogen activator, urokinase receptor

    Omim ID

    173391

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq

    Other Designations

    monocyte activation antigen Mo3|u-plasminogen activator receptor form 2

  • Interactome
  • Pathway
  • Disease