SCB-4380
Référence orb1910641-250mg
Conditionnement : 250mg
Marque : Biorbyt
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SCB-4380
Catalog Number: orb1910641
| Catalog Number | orb1910641 |
|---|---|
| Category | Small Molecules |
| Description | SCB-4380 (SCB 4380, SCB4380) is the first potent, selective inhibitor for PTPRZ (protein tyrosine phosphatase receptor-type Z) with IC50 of 0.4 uM against human Z-ICR-catalyzed hydrolysis. SCB-4380 also strongly inhibits PTPRG (IC50=0.4 uM), and shows little inhibition on PTPRA, PTPRM, PTPRS, PTPRB, PTPN1 and PTPN6. SCB-4380 inhibites PTPRZ activity in C6 glioblastoma cells, and suppresse cell migration and proliferation in vitro and tumor growth in a rat allograft model. |
| CAS Number | [915-67-3] |
| MW | 604.473054170609 |
| SMILES | [Na+].[Na+].[Na+].C1=C2C(C=CC(S([O-])(=O)=O)=C2)=C(/N=N/C2=C3C(C=CC=C3)=C(S([O-])(=O)=O)C=C2)C(O)=C1S([O-])(=O)=O |
| Formula | C20H11N2NA3O10S3 |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |