siTran 2.0 siRNA transfection reagent (0.5 ml)
Référence TT320001
Conditionnement : 500ul
siTran 2.0 siRNA transfection reagent (0.5 ml)
SKU
TT320001
siTran 2.0 siRNA transfection reagent (0.5ml)
Citations
Fusobacterium nucleatum plays a pathogenic role in a murine model of irritable bowel syndrome by modulating intestinal purine metabolism and promoting mast cell activation
Hou, Ning, Liu et al
Gut Microbes (2026) 18 (1), 2620124 DOI: 10.1080/19490976.2026.2620124
Hou, Ning, Liu et al
Gut Microbes (2026) 18 (1), 2620124 DOI: 10.1080/19490976.2026.2620124
Cited by 4
AI Summary: OriGene’s siTran 2.0 transfection reagent (TT320001) was used to deliver siRNA targeting purine nucleoside phosphorylase (PNP) in intestinal epithelial cells, enabling the study of PNP’s role in Fusobacterium nucleatum-induced IBS-like symptoms in mice.
Snippet: nces targeting PNP were as follows: siPNP sense: 5′-GAUCUUUGACUACGGUGAA-3′;siPNP antisense: 5′-UUCACCGUAGUCAAAGAUC-3′. Transfection was carried out with siTran 2.0 (TT320001, Origene).Peritoneal mast cell cultures (PMCs)Peritoneal cells isolated from C57BL/6 mice aged 6–10 weeks were cultured in RPMI164
Lutein Attenuates Lipid Accumulation in Association with TFEB Nuclear Translocation and Autophagy-Lysosomal Responses in a Cellular Model of Hepatic Steatosis
Saud, Cabrera, Valladares et al
Antioxidants (Basel) (2026) 15 (8) DOI: 10.3390/antiox15081042
Saud, Cabrera, Valladares et al
Antioxidants (Basel) (2026) 15 (8) DOI: 10.3390/antiox15081042
AI Summary: In this study, OriGene products—including the TFEB Human siRNA Oligo Duplex and the siTran 2.0 siRNA transfection reagent—were used to specifically silence TFEB expression in HepG2 cells, enabling the authors to investigate the role of TFEB in lutein’s lipid-lowering and autophagy-related effects.
Snippet: d transfected at 60–70% confluence with a non-targeting control siRNA (siRNA-nt) or with one of three independent siRNA sequences targeting human TFEB (TFEB Human siRNA Oligo Duplex (Locus ID 7942, OriGene Technologies (Rockville, MD, USA))). using siTran 2.0 siRNA transfection reagent (TT320001, Origene), according to the manufacturer’s instructions. Silencing efficiency was determined 48 h p
Role of cystathionine β-synthase in modulating NO and H₂S signaling under metabolic stress in obesity-driven endothelial dysfunction
Esposito, Indolfi, Pirozzi et al
Life Sci (2026) 398, 124448 DOI: 10.1016/j.lfs.2026.124448
Esposito, Indolfi, Pirozzi et al
Life Sci (2026) 398, 124448 DOI: 10.1016/j.lfs.2026.124448
AI Summary: OriGene's siTran 0.0 Transfection Reagent (Cat. No. TT320001) was used to deliver CBS-targeting siRNA into endothelial cells, enabling the study of CBS's role in modulating NO and H₂S signaling under metabolic stress.
Snippet: … No. TT320001, OriGene, Rockville, MD, USA). …
The effect of dehydroepiandrosterone on the vascular system: role of H2S/NO pathways
Turnaturi, Indolfi, Correale et al
Eur J Pharmacol (2026) 1026, 178957 DOI: 10.1016/j.ejphar.2026.178957
Turnaturi, Indolfi, Correale et al
Eur J Pharmacol (2026) 1026, 178957 DOI: 10.1016/j.ejphar.2026.178957
AI Summary: OriGene’s siTran 0.0 Transfection Reagent (Cat. No. TT320001) was used to transfect bovine aortic endothelial cells (BAEC), enabling the study of DHEA’s effects on vascular function in this research.
Snippet: BAEC were seeded into 6-well plates (5 × 103 cell/well) and once 70–80% of confluence had been reached, were transfected according to the manufacturer's instructions using the siTran 0.0 Transfection Reagent (Cat. No. TT320001, OriGene, Rockville, MD, USA)
Spinal P2X3 receptors blockade reverses paclitaxel-induced allodynia in rats
Segura-Chama, Ramos-Chávez, Yañez-Recendis et al
Purinergic Signal (2026) 22 (1), 10 DOI: 10.1007/s11302-025-10120-8
Segura-Chama, Ramos-Chávez, Yañez-Recendis et al
Purinergic Signal (2026) 22 (1), 10 DOI: 10.1007/s11302-025-10120-8
Cited by 1
AI Summary: In this study, OriGene products—including P2X3 siRNA (cat. SR505971), Duplex Resuspension Buffer (cat. SR30005), and siTran 2.0 siRNA transfection reagent (cat. TT320001)—were used to transiently knock down P2X3 receptor expression in rats, enabling the researchers to assess the role of these receptors in paclitaxel-induced allodynia.
Snippet: d from OriGene Technologies Inc., Rockville, MD, USA (cat. SR505971), siRNA was diluted in Duplex Resuspension Buffer (cat. SR30005) and prepare for transfection with the siTran 2.0 siRNA transfection reagent (TT320001) following the manufacturer instructions;siR
Oxytocin regulation of intestinal stem cell self-renewal and differentiation
Liu, Guo, Geng et al
Cell Signal (2025) 139, 112337 DOI: 10.1016/j.cellsig.2025.112337
Liu, Guo, Geng et al
Cell Signal (2025) 139, 112337 DOI: 10.1016/j.cellsig.2025.112337
Cited by 2
AI Summary: OriGene products contributed to this study by providing the siTran 2.0 siRNA transfection reagent (TT320001), siRNA targeting Ptger4 (SR415743), and control siRNA (SR30002), which were used to investigate the role of EP4 in oxytocin-mediated intestinal stem cell regulation.
Snippet: Small interfering RNA (siRNA) transfections were carried out with siTran 2.0 siRNA transfection reagent (Origene, TT320001) according to the manufacturer's instructions. The organoids were transfected with siRNA Ptger4 (Origene, SR415743) or siRNA control (Origene, SR30002)
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