- Specifications
Product Description
Tissue Factor (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human Tissue Factor.
Suitable Sample
Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Extracts
Sample Volume
50 uL
Label
Peroxidase-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
12.5 to 400 pg/mL
Limit of Detection
3.3 pg/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store components of the kit at 4°C or -20°C as described in the protocol.
- Applications
Quantification
- Gene Info — F3
Entrez GeneID
2152Gene Name
F3
Gene Alias
CD142, TF, TFA
Gene Description
coagulation factor III (thromboplastin, tissue factor)
Omim ID
134390Gene Ontology
HyperlinkGene Summary
This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. [provided by RefSeq
Other Designations
OTTHUMP00000012426|coagulation factor III|tissue factor
- Interactomes
- Pathways
- Diseases
- Publication Reference
- Myeloid-related protein-8/14 in acute coronary syndrome.
Sakuma M, Tanaka A, Kotooka N, Hikichi Y, Toyoda S, Abe S, Taguchi I, Node K, Simon DI, Inoue T.
International Journal of Cardiology 2017 Dec; 249:25.
Application：Quant, Human, HUVEC.
- Tissue factor in cancer angiogenesis and metastasis.
Ruf W, Mueller BM.
Current Opinion in Hematology 1996 Sep; 3(5):379.
Application：Quant, Human, Keratinocytes, Monocytes, Tumor cells, Vascular endothelial cells.
- Role of tissue factor in embryonic blood vessel development.
Carmeliet P, Mackman N, Moons L, Luther T, Gressens P, Van Vlaenderen I, Demunck H, Kasper M, Breier G, Evrard P, Muller M, Risau W, Edgington T, Collen D.
Nature 1996 Sep; 383(6595):73.
- Tissue factor controls the balance of angiogenic and antiangiogenic properties of tumor cells in mice.
Zhang Y, Deng Y, Luther T, Muller M, Ziegler R, Waldherr R, Stern DM, Nawroth PP.
The Journal of Clinical Investigation 1994 Sep; 94(3):1320.
- Myeloid-related protein-8/14 in acute coronary syndrome.
Tissue Factor (Human) ELISA Kit
Référence KA0506
Conditionnement : 1Kit
Marque : Abnova
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Téléphone : +1 850 650 7790