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> TNF beta Protein, Human, Recombinant (His)

TNF beta Protein, Human, Recombinant (His)

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Référence NB-64-50296-1mg

Conditionnement : 1mg

Marque : Neo Biotech


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TNF beta Protein, Human, Recombinant (His)

(Synonyms: Tumor necrosis factor ligand superfamily member 1, TNFSF1, TNF-beta, TNFB, Lymphotoxin-alpha, LT-alpha, LTA) Copy Product Info

Synonyms: Tumor necrosis factor ligand superfamily member 1, TNFSF1, TNF-beta, TNFB, Lymphotoxin-alpha, LT-alpha, LTA

Catalog No. TMPH-01620 Copy Product Info
Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
Other Forms of TNF beta Protein, Human, Recombinant (His):
TNF beta Protein, Mouse, Recombinant (His)
TNF beta Protein, Human, Recombinant
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95%(SDS-PAGE)
Appearance:Lyophilized powder
Color:White
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Product Information

Bioactivity
Bioactivity
1. Measured by its binding ability in a functional ELISA. Immobilized LTA at 5 μg/mL can bind human TNFRSF1B, the EC 50 is 1.632-2.699 ng/mL.
2. Measured by its binding ability in a functional ELISA. Immobilized LTA at 5 μg/mL can bind human TNFR1, the EC 50 of human LTA protein is 4.409-6.797 ng/mL.
Description
Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
Species
Human
Expression System
HEK293 Cells
TagN-6xHis
Accession NumberP01374
Amino AcidLPGVGLTPSAAQTARQHPKMHLAHSTLKPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLSNNSLLVPTSGIYFVYSQVVFSGKAYSPKATSSPLYLAHEVQLFSSQYPFHVPLLSSQKMVYPGLQEPWLHSMYHGAAFQLTQGDQLSTHTDGIPHLVLSPSTVFFGAFAL
Construction35-205 aa
Protein Purity
> 95% as determined by SDS-PAGE.
TNF beta Protein, Human, Recombinant (His)
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a 0.2 μm sterile filtered 20 mM Tris-HCl,0.5 M NaCl, 6% Trehalose, pH 8.0
ReconstitutionReconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsTumor necrosis factor ligand superfamily member 1, TNFSF1, TNF-beta, TNFB, Lymphotoxin-alpha, LT-alpha, LTA
Research Background
Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
Chemical Properties
Molecular Weight20.8 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

TNF-βTNFβTNFSF 1TNF-bLymphotoxin-αLymphotoxinαLymphotoxin-aLT-αLTαLT-a
Related Tags: TNF beta Protein, Human, Recombinant (His) chemical structure | TNF beta Protein, Human, Recombinant (His) molecular weight