TNFAIP3 (NM_006290) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC221337L3V

  • LentiORF®

Lenti ORF particles, TNFAIP3 (Myc-DDK tagged) - Human tumor necrosis factor, alpha-induced protein 3 (TNFAIP3), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK DDK w/ Puro mGFP mGFP w/ Puro


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Product Images

Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol TNFAIP3
Synonyms A20; AISBL; OTUD7C; TNFA1P2
Mammalian Cell Selection Puromycin
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_006290
ORF Size 2370 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC221337).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_006290.3
RefSeq Size 4705 bp
RefSeq ORF 2373 bp
Locus ID 7128
UniProt ID P21580
Cytogenetics 6q23.3
Domains zf-A20
Protein Families Druggable Genome
Protein Pathways NOD-like receptor signaling pathway
MW 90.1 kDa
Gene Summary This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2012]