TSH alpha, CT (CGA, Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Choriogonadotropin alpha chain, Chorionic gonadotrophin subunit alpha, Follicle-stimulating hormone alpha chain, Follitropin alpha chain,
Référence MBS6359483-5x0,1mL
Conditionnement : 5x0.1mL
Marque : MyBiosource
TSH Alpha (CGA) Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6359483The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha… More details
Product Overview
Online Datasheet in PDFProduct Name
TSH alpha (CGA), Polyclonal Antibody
Full Product Name
TSH alpha, CT (CGA, Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Choriogonadotropin alpha chain, Chorionic gonadotrophin subunit alpha, Follicle-stimulating hormone alpha chain, Follitropin alpha chain
Product Gene Name
anti-CGA antibody
Product Synonym Names
CGA; Glycoprotein hormones alpha chain; Anterior pituitary glycoprotein hormones common subunit alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; Follicle-stimulating hormone alpha chain; Follitropin alpha chain; Luteinizing hormone alpha chain; Lutropin alpha chain; Thyroid-stimulating hormone alpha chain; Thyrotropin alpha chain
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.
Purity/Purification
Purified by Protein A and Peptide Affinity Chromatography.
Specificity
Recognizes human TSH alpha.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
10kDa
OMIM
118850
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 74-103 in the C-terminal region of human TSH alpha, UniProt Accession #P01215.
Conjugate
MaxLight750
Note
Preservative Free
Product Categories/Family for anti-CGA antibody
Antibodies; Carbohydrates; Glycoproteins
Applications Tested/Suitable for anti-CGA antibody
Western Blot (WB), FLISA
Application Notes for anti-CGA antibody
Applications are based on unconjugated antibody.
Product References and Citations for anti-CGA antibody
1. Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884 (2010). 2. Panicker, V., et al. Am. J. Hum. Genet. 87(3):430-435 (2010). 3. Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010). 4. Robinson, N., et al. Clin. Lab. 56 (5-6), 197-206 (2010). 5. Bjerner, J., et al. Scand. J. Clin. Lab. Invest. 69(8):873-879(2009).
Other Notes
Small volumes of anti-CGA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for CGA purchase
MBS6359483 is an antibody targeting CGA. Also known as TSH alpha, CT (CGA, Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Choriogonadotropin alpha chain, Chorionic gonadotrophin subunit alpha, Follicle-stimulating hormone alpha chain, Follitropin alpha chain. Reactive in Human. Host: Rabbit.
Additional Details
NCBI/Uniprot data below describe general gene information for CGA. It may not necessarily be applicable to this product.
NCBI Official Full Name
thyroid-stimulating hormone alpha subunit
NCBI Official Synonym Full Names
glycoprotein hormones, alpha polypeptide
NCBI Official Symbol
CGA
NCBI Official Synonym Symbols
HCG; LHA; FSHA; GPHa; TSHA; GPHA1; CG-ALPHA
UniProt Protein Name
Glycoprotein hormones alpha chain
UniProt Synonym Protein Names
Anterior pituitary glycoprotein hormones common subunit alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; CG-alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; Luteinizing hormone alpha chain; LSH-alpha; Lutropin alpha chain; Thyroid-stimulating hormone alpha chain; TSH-alpha; Thyrotropin alpha chain
Protein Family
Glycoprotein hormones
UniProt Gene Name
CGA
UniProt Synonym Gene Names
CG-alpha; FSH-alpha; LSH-alpha; TSH-alpha
UniProt Entry Name
GLHA_HUMAN
NCBI Protein Information
glycoprotein hormones alpha chain
NCBI Summary for CGA
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Show more UniProt Comments for CGA
CGA: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 6q12-q21
Cellular Component: extracellular region
Molecular Function: protein binding; hormone activity
Biological Process: cellular protein metabolic process; cell-cell signaling; peptide hormone processing; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; signal transduction; positive regulation of cell migration
Show more Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 6q12-q21
Cellular Component: extracellular region
Molecular Function: protein binding; hormone activity
Biological Process: cellular protein metabolic process; cell-cell signaling; peptide hormone processing; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; signal transduction; positive regulation of cell migration
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-CGA antibody
| Reference Product | PubMed Publications |
|---|---|
| LHB antibody | >28 publications with CGA and LHB |
| FSHB antibody | >27 publications with CGA and FSHB |
| FSHR antibody | >6 publications with CGA and FSHR |
| TSHB antibody | >3 publications with CGA and TSHB |
| LHCGR antibody | >2 publications with CGA and LHCGR |
| CGB8 antibody | >1 publications with CGA and CGB8 |
Pathways associated with anti-CGA antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Amine-derived Hormones Pathway antibodies | Amine-derived Hormones Pathway Diagram |
| Androgen Biosynthesis Pathway antibodies | Androgen Biosynthesis Pathway Diagram |
| Autoimmune Thyroid Disease Pathway antibodies | Autoimmune Thyroid Disease Pathway Diagram |
| Autoimmune Thyroid Disease Pathway antibodies | Autoimmune Thyroid Disease Pathway Diagram |
| Class A/1 (Rhodopsin-like Receptors) Pathway antibodies | Class A/1 (Rhodopsin-like Receptors) Pathway Diagram |
| FSH Signaling Pathway antibodies | FSH Signaling Pathway Diagram |
| G Alpha (s) Signalling Events Pathway antibodies | G Alpha (s) Signalling Events Pathway Diagram |
| GPCR Downstream Signaling Pathway antibodies | GPCR Downstream Signaling Pathway Diagram |
| GPCR Ligand Binding Pathway antibodies | GPCR Ligand Binding Pathway Diagram |
| Glucocorticoid Receptor Regulatory Network Pathway antibodies | Glucocorticoid Receptor Regulatory Network Pathway Diagram |
Diseases associated with anti-CGA antibody
| Disease Name | Pubmed Publications |
|---|---|
| Neoplasms Antibodies | >872 publications with CGA and Neoplasms |
| Adenocarcinoma Antibodies | >267 publications with CGA and Adenocarcinoma |
| Nervous System Diseases Antibodies | >164 publications with CGA and Nervous System Diseases |
| Prostatic Diseases Antibodies | >130 publications with CGA and Prostatic Diseases |
| Prostatic Neoplasms Antibodies | >129 publications with CGA and Prostatic Neoplasms |
| Lung Neoplasms Antibodies | >112 publications with CGA and Lung Neoplasms |
| Brain Diseases Antibodies | >111 publications with CGA and Brain Diseases |
| Cardiovascular Diseases Antibodies | >102 publications with CGA and Cardiovascular Diseases |
| Disease Progression Antibodies | >93 publications with CGA and Disease Progression |
| Hyperplasia Antibodies | >76 publications with CGA and Hyperplasia |
Organs/Tissues associated with anti-CGA antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >165 publications with CGA and Brain |
| Lung Antibodies | >159 publications with CGA and Lung |
| Stomach Antibodies | >131 publications with CGA and Stomach |
| Liver Antibodies | >128 publications with CGA and Liver |
| Thyroid Antibodies | >102 publications with CGA and Thyroid |
| Heart Antibodies | >99 publications with CGA and Heart |
| Muscle Antibodies | >97 publications with CGA and Muscle |
| Vascular Antibodies | >92 publications with CGA and Vascular |
| Pituitary Gland Antibodies | >71 publications with CGA and Pituitary Gland |
| Skin Antibodies | >55 publications with CGA and Skin |