1-Aminocyclopropane-1-carboxylic acid [22059-21-8]
Katalog-Nummer T4752-500mg
Size : 500mg
Marke : TargetMol
1-Aminocyclopropane-1-carboxylic acid
(Synonyms: ACC, 1-Aminocyclopropanecarboxylic acid, 1-Amino-1-carboxycyclopropane) Copy Product Info
1-Aminocyclopropane-1-carboxylic acid (ACC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. It is a small molecule agonist at the glycine modulatory site of the NMDA receptor (EC50 = 0.7-0.9 μM) in the presence of low levels (1 μM) of glutamate and as a competitive antagonist at the glutamate-binding site on NMDA receptors (EC50 = 81.6 nM) with high levels (10 μM) of glutamate.2 This compound has been reported to protect against neuron cell death in vivo models of ischemia by enabling moderate levels of NMDA receptor activation and attenuating any excess NMDA receptor signaling that may lead to neurotoxicity.
Cas No. 22059-21-8
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.93%
Appearance:Solid
Color:White
COA HNMR LCMS
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | 1-Aminocyclopropane-1-carboxylic acid (ACC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. It is a small molecule agonist at the glycine modulatory site of the NMDA receptor (EC50 = 0.7-0.9 μM) in the presence of low levels (1 μM) of glutamate and as a competitive antagonist at the glutamate-binding site on NMDA receptors (EC50 = 81.6 nM) with high levels (10 μM) of glutamate.2 This compound has been reported to protect against neuron cell death in vivo models of ischemia by enabling moderate levels of NMDA receptor activation and attenuating any excess NMDA receptor signaling that may lead to neurotoxicity. |
| Targets & IC50 | NMDAR:0.7-0.9 µM (EC50) |
| Synonyms | ACC, 1-Aminocyclopropanecarboxylic acid, 1-Amino-1-carboxycyclopropane |
| Molecular Weight | 101.104 |
| Formula | C4H7NO2 |
| Cas No. | 22059-21-8 |
| Smiles | NC1(C(=O)O)CC1 |
| Relative Density. | 1.414g/cm3 |
| Storage | Keep away from direct sunlight,Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 100.00 mg/mL (989.08 mM), Sonication is recommended.  DMSO: Insoluble | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||||||||||||