Anti-AGT Antibody (4U964)
Katalog-Nummer NB-64-119731-100uL
Size : 100uL
Marke : Neo Biotech
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Anti-AGT Antibody (4U964)
(Synonyms: SERPINA8, Serpin A8, Angiotensinogen, AGT) Copy Product InfoSynonyms: SERPINA8, Serpin A8, Angiotensinogen, AGT
Catalog No. TMAH-00039 Copy Product Info
Anti-AGT Antibody (4U964) is an antibody targeting AGT. Anti-AGT Antibody (4U964) can be used in ELISA,IHC.
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Information
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-AGT Antibody (4U964) is an antibody targeting AGT. Anti-AGT Antibody (4U964) can be used in ELISA,IHC. |
| Synonyms | SERPINA8, Serpin A8, Angiotensinogen, AGT |
| Ig Type | Rabbit IgG |
| Clone | 4U964 |
| Reactivity | Human |
| Verified Activity | IHC image of TMAH-00039 diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| Application | ELISA IHC |
| Recommended Dose | IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone. stimulates aldosterone release. is a ligand for the G-protein coupled receptor MAS1. Has vasodilator and antidiuretic effects. Has an antithrombotic effect that involves MAS1-mediated release of nitric oxide from platelets. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human Angiotensinogen |
| Antigen Species | Human |
| Gene Name | AGT |
| Gene ID | 183 |
| Uniprot ID | P01019 |
| Biology Area | Cardiovascular, Metabolism, Signal transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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