Anti-EMR3 Polyclonal Antibody
Katalog-Nummer NB-64-155511-50uL
Size : 50uL
Marke : Neo Biotech
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Anti-EMR3 Polyclonal Antibody
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Catalog No. TMAB-05559 Copy Product Info
Anti-EMR3 Polyclonal Antibody is a Rabbit antibody targeting EMR3. Anti-EMR3 Polyclonal Antibody can be used in WB.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-EMR3 Polyclonal Antibody is a Rabbit antibody targeting EMR3. Anti-EMR3 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human) |
| Verified Activity | Sample: Thymus (Mouse) Lysate at 40 μg Primary: Anti-EMR3 (TMAB-05559) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 70 kD Observed band size: 70 kD |
| Application | WB |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. EMR3 subunit alpha: Secreted, extracellular space. Note: A soluble form is also detected. |
| Tissue Specificity | Displays a predominantly leukocyte-restricted expression, with highest levels in neutrophils, monocytes and macrophages. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human EMR3 |
| Antigen Species | Human |
| Gene Name | ADGRE3 |
| Gene ID | 84658 |
| Protein Name | Adhesion G protein-coupled receptor E3 |
| Uniprot ID | Q9BY15 |
| Function | EMR3 is a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing of this gene results in two transcript variants encoding two distinct isoforms. EMR3 has been reported to be expressed in neutrophils, monocytes, and macrophages. ESTs have been isolated from liver/spleen and mixed libraries. |
| Molecular Weight | Theoretical: 70 kDa. Actual: 70 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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