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Anti-GATA4 Polyclonal Antibody

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Katalog-Nummer NB-64-156308-100uL

Size : 100uL

Marke : Neo Biotech


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Anti-GATA4 Polyclonal Antibody

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Synonyms:

Catalog No. TMAB-06358 Copy Product Info
Anti-GATA4 Polyclonal Antibody is a Rabbit antibody targeting GATA4. Anti-GATA4 Polyclonal Antibody can be used in WB.
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Information

Bioactivity
Description
Anti-GATA4 Polyclonal Antibody is a Rabbit antibody targeting GATA4. Anti-GATA4 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Rabbit)
Verified Activity
Sample: Small intestine (Mouse) Lysate at 40 μg
Primary: Anti-GATA4 (TMAB-06358) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 49 kD
Observed band size: 49 kD
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundGATA4 is a 46 kDa member of the GATA family of zinc finger containing transcription factors that is involved in the development of cardiac hypertrophy and remodeling, and plays a critical role in regulating basal and agonist or stress induced gene expression in cardiac and smooth muscle cell types. GATA4 contains a conserved MAPK phosphorylation site at serine 105 within the transcriptional activation domain. Serine 105 of GATA4 is phosphorylated in response to agonist stimulation through MEK 1 ERK1 / 2, and weakly through JNK or p38 MAPKs.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human GATA4
Antigen Species
Human
Gene Name
GATA4
Gene ID
2626
Protein Name
Transcription factor GATA-4
Uniprot ID
P43694
Function
Transcriptional activator. Binds to the consensus sequence 5'-AGATAG-3'. Acts as a transcriptional activator of ANF in cooperation with NKX2-5 (By similarity). Promotes cardiac myocyte enlargement.
Chemical Properties
Molecular WeightTheoretical: 49 kDa. Actual: 49 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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