BING TFA
Katalog-Nummer T83705-10mg
Size : 10mg
Marke : TargetMol
BING TFA
(Synonyms: Blocker of Inter-membrane Stress Responses of Gram-negative Bacteria) Copy Product InfoBING, a antimicrobial peptide discovered in Japanese medaka fish (O. laptipes), originates from vacuolar protein sorting-associated protein 13D-like (Vps13D). It exhibits efficacy against a range of Gram-negative and Gram-positive bacteria, notably including methicillin-resistant S. aureus (MRSA; MICs = 4-64 µg/ml). Furthermore, BING enhances the effectiveness of antibiotics such as ampicillin, amoxicillin, and novobiocin against P. aeruginosa, and it prevents resistance development to kanamycin and ampicillin in E. coli. Notably, its administration in vivo significantly improves survival rates in O. laptipes challenged with E. tarda.
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | BING, a antimicrobial peptide discovered in Japanese medaka fish (O. laptipes), originates from vacuolar protein sorting-associated protein 13D-like (Vps13D). It exhibits efficacy against a range of Gram-negative and Gram-positive bacteria, notably including methicillin-resistant S. aureus (MRSA; MICs = 4-64 µg/ml). Furthermore, BING enhances the effectiveness of antibiotics such as ampicillin, amoxicillin, and novobiocin against P. aeruginosa, and it prevents resistance development to kanamycin and ampicillin in E. coli. Notably, its administration in vivo significantly improves survival rates in O. laptipes challenged with E. tarda. |
| Synonyms | Blocker of Inter-membrane Stress Responses of Gram-negative Bacteria |
| Molecular Weight | 1464.84 |
| Formula | C67H125N21O15.XCF3COOH |
| Smiles | OC(C(F)(F)F)=O.CC[C@H](C)[C@H](N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(NCC(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@H](C(O)=O)[C@@H](C)CC)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O |
| Sequence | H-Ile-Arg-Ile-Ile-Leu-Arg-Ala-Gln-Gly-Ala-Leu-Lys-Ile-OH |
| Sequence Short | IRIILRAQGALKI |
| Storage | Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO: Slightly soluble DMF: Slightly soluble |


