BLIMP1/PRDM1 Antibody Polyclonal
Catalog Number: B2016823 (10 µl)
BLIMP1/PRDM1 Antibody Polyclonal is a high quality transcriptional repressor protein that plays a critical role in regulating gene expression in various cell types, including immune cells. An antibody targeting BLIMP1/PRDM1 would be used in research to detect and study the expression and localization of this protein in cells or tissues. The antibody would specifically bind to BLIMP1/PRDM1, allowing researchers to visualize and quantify its presence in samples using techniques such as immunohistochemistry, immunofluorescence, or Western blotting. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.
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Product Description
BLIMP1/PRDM1 Antibody Polyclonal
Catalog number: B2016823
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 µl
Molecular Weight or Concentration: 110 kDa
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: PRDI-BF1
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
References:
1: Gonzalez-Figueroa P, Roco JA, Papa I, Núñez Villacís L, Stanley M, Linterman MA, Dent A, Canete PF, Vinuesa CG. Follicular regulatory T cells produce neuritin to regulate B cells Cell. 2021 Apr 1;184(7):1775-1789.e19.
2: Nadeau S, Martins GA. Conserved and Unique Functions of Blimp1 in Immune Cells Front Immunol. 2022 Jan 27;12:805260.
3: Rao DA, Gurish MF, Marshall JL, Slowikowski K, Fonseka CY, Liu Y, Donlin LT, Henderson LA, Wei K, Mizoguchi F, Teslovich NC, Weinblatt ME, Massarotti EM, Coblyn JS, Helfgott SM, Lee YC, Todd DJ, Bykerk VP, Goodman SM, Pernis AB, Ivashkiv LB, Karlson EW, Nigrovic PA, Filer A, Buckley CD, Lederer JA, Raychaudhuri S, Brenner MB. Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis Nature. 2017 Feb 1;542(7639):110-114.
4: Yang M, Long D, Hu L, Zhao Z, Li Q, Guo Y, He Z, Zhao M, Lu L, Li F, Long H, Wu H, Lu Q. AIM2 deficiency in B cells ameliorates systemic lupus erythematosus by regulating Blimp-1-Bcl-6 axis-mediated B-cell differentiation Signal Transduct Target Ther. 2021 Sep 14;6(1):341.
5: Wöhner M, Pinter T, Bönelt P, Hagelkruys A, Kostanova-Poliakova D, Stadlmann J, Konieczny SF, Fischer M, Jaritz M, Busslinger M. The Xbp1-regulated transcription factor Mist1 restricts antibody secretion by restraining Blimp1 expression in plasma cells Front Immunol. 2022 Dec 21;13:859598.
6: Moroney JB, Chupp DP, Xu Z, Zan H, Casali P. Epigenetics of the antibody and autoantibody response Curr Opin Immunol. 2020 Dec;67:75-86.
7: Torres M, Dickson AJ. Overexpression of transcription factor BLIMP1/prdm1 leads to growth inhibition and enhanced secretory capacity in Chinese hamster ovary cells Metab Eng. 2021 Sep;67:237-249.
8: Qing K, Jin Z, Xu Z, Wang W, Li X, Zhang Y, Wang L, Zhu H, Xiang R, Wu S, Li R, Jiang G, Xue K, Li J. Dysregulated MDR1 by PRDM1/Blimp1 Is Involved in the Doxorubicin Resistance of Non-Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma Chemotherapy. 2022;67(1):12-23.
9: Tang TF, Chan YT, Cheong HC, Cheok YY, Anuar NA, Looi CY, Gan GG, Wong WF. Regulatory network of BLIMP1, IRF4, and XBP1 triad in plasmacytic differentiation and multiple myeloma pathogenesis Cell Immunol. 2022 Oct;380:104594.
10: D’Costa K, Emslie D, Metcalf D, Smyth GK, Karnowski A, Kallies A, Nutt SL, Corcoran LM. Blimp1 is limiting for transformation in a mouse plasmacytoma model Blood. 2009 Jun 4;113(23):5911-9.
Products Related to BLIMP1/PRDM1 Antibody Polyclonal can be found at Antibodies
Additional Information
| Weight | 0.15 oz |
|---|---|
| Dimensions | 2 × 0.5 × 0.5 in |