DMG-PEG 2000 [160743-62-4]
Katalog-Nummer NB-64-45449-100mg
Size : 100mg
Marke : Neo Biotech
DMG-PEG 2000 (Synonyms: DMG-PEG2000)
Catalog No. T9098 Copy Product Info
DMG-PEG2000 (DMG-PEG2000) can be used for the preparation of lipid nanoparticles for oral delivery of plasmid DNA in vivo to improve the mucus permeability and delivery efficiency of nanoparticles. DMG-PEG 2000 can be used for the preparation of siRNA transfected liposomes, which can improve the transfection efficiency.
DMG-PEG 2000
Copy Product InfoSynonyms DMG-PEG2000
DMG-PEG2000 (DMG-PEG2000) can be used for the preparation of lipid nanoparticles for oral delivery of plasmid DNA in vivo to improve the mucus permeability and delivery efficiency of nanoparticles. DMG-PEG 2000 can be used for the preparation of siRNA transfected liposomes, which can improve the transfection efficiency.
Cas No. 160743-62-4
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Purity:≥98%
Appearance:Solid
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | DMG-PEG2000 (DMG-PEG2000) can be used for the preparation of lipid nanoparticles for oral delivery of plasmid DNA in vivo to improve the mucus permeability and delivery efficiency of nanoparticles. DMG-PEG 2000 can be used for the preparation of siRNA transfected liposomes, which can improve the transfection efficiency. |
| In vivo | METHODS: To study the permeability of NP-3, a single dose of NP-3 (150 μg DNA per mouse) was administered orally to mice. RESULTS: The NP-3 group maintained high luciferase expression in the liver, lung, and intestinal regions within 12 to 24 hours after administration. In addition, NP-3 showed a 1.5-fold higher signal intensity than the NP-1 or NP-2 groups within 12 to 24 hours after oral administration. [1] |
| Synonyms | DMG-PEG2000 |
| Molecular Weight | 2526 |
| Formula | (C2H4O)nC32H62O5 |
| Cas No. | 160743-62-4 |
| Smiles | N.CCCCCCCCCCCCCC(=O)OCC(COCCOC)OC(=O)CCCCCCCCCCCCC |
| Relative Density. | no data available |
| Storage | ||||||||||||||||||||||||||
| Solubility Information | Ethanol: 100 mg/mL (39.59 mM), Sonication is recommended.  DMSO: 60 mg/mL (23.75 mM), Sonication is recommended. | |||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (0.79 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO/Ethanol
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||
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