Reagenzien und Instrumente für die Immunologie Zellbiologie und Molekularbiologie
 
> Frizzled 4 Protein, Human, Recombinant (hFc)

Frizzled 4 Protein, Human, Recombinant (hFc)

Drucken Drucken
Melden Sie sich an

Katalog-Nummer NB-64-55429-5ug

Size : 5ug

Marke : Neo Biotech


Remove All

Frizzled 4 Protein, Human, Recombinant (hFc)

(Synonyms: hFz4, GPCR, FzE4, FZD4S, Fz-4, Fz4, frizzled class receptor 4, FEVR, EVR1, CD344) Copy Product Info

Synonyms: hFz4, GPCR, FzE4, FZD4S, Fz-4, Fz4, frizzled class receptor 4, FEVR, EVR1, CD344

Catalog No. TMPY-00197 Copy Product Info
Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known to cause autosomal dominant exudative vitreoretinopathy (EVR1). The mutations in FZD4 are associated with the phenotypes of retinal folds or ectopic macula in FEVR. Frizzled 4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.3 kDa and the accession number is Q9ULV1.
Other Forms of Frizzled 4 Protein, Human, Recombinant (hFc):
LRP-5 Protein, Human, Recombinant (hFc)
LRP-5 Protein, Human, Recombinant (mFc)
Frizzled 4 Protein, Rat, Recombinant (His)
Frizzled 4 Protein, Rat, Recombinant (hFc)
Frizzled 4 Protein, Human, Recombinant (His)
LRP-5 Protein, Human, Recombinant (His)
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Information

Bioactivity
Bioactivity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known to cause autosomal dominant exudative vitreoretinopathy (EVR1). The mutations in FZD4 are associated with the phenotypes of retinal folds or ectopic macula in FEVR. Frizzled 4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.3 kDa and the accession number is Q9ULV1.
Species
Human
Expression System
HEK293 Cells
TagC-hFc
Accession NumberQ9ULV1
ConstructionA DNA sequence encoding the human FZD4 (NP_036325.2) (Met1-Glu180) was expressed with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Phe 37
Protein Purity
> 95 % as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
SynonymshFz4, GPCR, FzE4, FZD4S, Fz-4, Fz4, frizzled class receptor 4, FEVR, EVR1, CD344
Research Background
Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known to cause autosomal dominant exudative vitreoretinopathy (EVR1). The mutations in FZD4 are associated with the phenotypes of retinal folds or ectopic macula in FEVR
Chemical Properties
Molecular Weight43.3 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Calculator

  • Reconstitution Calculator
  • Recombinant Protein Dilution Calculator
  • Specific Activity Calculator

Dose Conversion

Keywords

EVR-1EVR 1CD-344CD 344
Related Tags: Frizzled 4 Protein, Human, Recombinant (hFc) chemical structure | Frizzled 4 Protein, Human, Recombinant (hFc) molecular weight