Glycine max Lectin (SBA)
Katalog-Nummer L1216-50
Size : 50mg
Marke : GLYcoDiag
Glycine Max lectin (SBA)
| Reference | Short Name | Common Name | Inhibitory Carbohydrate | Glycans Structures Specifities |
|---|---|---|---|---|
| L1216 | SBA | Glycine Max | N-acetylgalactosamine. | D-GalNAc |
Glycine max lectin is isolated from soy bean (Soy bean agglutinin, SBA) and purified by affinity chromatography. The molecular weight of the lectin is 120 kDa, it consists of four identical subunits of 30 kDa each and it displays carbohydrate binding specifity for N-acetyl-D-galactosamine and galactopyranosyl residues of glycoproteins (1).
SBA has specificity for blood groups A1, A2 and B. The lectin interacts better with neuramidase-treated cells than with untreated cells. It has selective affinity for lymphocytes and human CD34+ hematopoietic stem cells. Immobilized conjugates of SBA are therefore important tools for removing T-cells in bone marrow transplantation. Glycine max lectin is supplied as a white to cream coloured lyophilized powder from a buffer containing 50 mM NH4HCO3, no preservatives are added. The material is made from a single production batch and is homogenous. It is not derived from any material of animal origin. The lectin is available in vials containing 50 mg or 10 mg lyophilized powder and the product is to be used for laboratory work only (2).
Applications
Studies of SBA-binding normal and tumour cells
Blood group agglutination
Glycoprotein studies
Cell agglutination studies
Features
Ultrapure quality
Binding specificity for N-acetyl-D-galactosamine
Specificity for blood group: A1 > A2 >> B
Lyophilized powder
Ordering informations
| Reference | Name | Quantity |
|---|---|---|
| L1216-50 | SBA lectin | 50 mg |
| L1216-10 | SBA lectin | 10 mg |
References
(1) Liener I. E., Sharon N., Goldstein I. J., (1986) The Lectins – Properties, Functions and Applications in Biology and Medicine.
(2) X-ray crystallographic studies of unique cross-linked lattices between four isomeric biantennary oligosaccharides and soybean agglutinin. Olsen, L.R., Dessen, A., Gupta, D., Sabesan, S., Sacchettini, J.C., Brewer, C.F. (1997) Biochemistry 36: 15073–80.
| Reference | Short Name | Common Name | Inhibitory Carbohydrate | Glycans Structures Specifities | |
|---|---|---|---|---|---|
| L1222 | ABA | Agaricus Bisporus | Gal/GalNAc | Gal(β-1,3) GaINAc | |
| L1221 | AIA / Jacalin | Artocarpus intergrifolia | Gal | Galα1-6 or Galβ1-3GalNAc (T-antigen)>> lactose, more specific for T-antigen than PNA | |
| L1367 | AML | Astragalus membranaceus | Gal | Galβ | |
| L1205 | ASA | Allium sativum agglutinin | α(1,3)Man | Mannose | |
| L1889 | BanLec | Musa acuminata | Mannose, Glucose | αMan | |
| L1255 | BC2L-A | Burkholderia cenocepacia | α(1,3)Man | Mannose-containing ligands | |
| L1256 | BC2L-C | Burkholderia cenocepacia | Lewis b / Lewis Y | Fucose containing ligands | |
| L1254 | CJA | Crotalaria juncea | lactose | Gal > GalNAc | |
| L1366 | cMol | Moringa oleifera | fetuin, thyroglobuline | GlcNAc, Complex carbohydrate-binding specificity | |
| L1201 | Con A | Concanavalin A | MeαMan | α-Man, Glc |
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