Human Glucosidase Alpha, Acid (GaA) Antibody Pair Kit (with Standard)

Katalog-Nummer MBS2098572-5x96

Size : 5x96Tests

Marke : MyBiosource


Glucosidase Alpha, Acid (GaA) Antibody Pair Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2098572
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MBS2098572 is an antibody pair kit targeting GaA. Also known as Human Glucosidase Alpha, Acid (GaA) Antibody Pair Kit (with Standard). Reactive in Human. More details

Product Overview

Online Datasheet in PDF
Product Name
Glucosidase Alpha, Acid (GaA), Antibody Pair Kit
Full Product Name
Human Glucosidase Alpha, Acid (GaA) Antibody Pair Kit (with Standard)
Product Gene Name
GaA antibody pair kit
Product Synonym Names
LYAG; Acid Alpha-Glucosidase; Lysosomal Alpha-Glucosidase; Pompe Disease Glycogen Storage Disease Type II; Acid Maltase; Aglucosidase Alfa
Species Reactivity
Human
Samples
Serum, Plasma, Tissue Homogenates, Cell Lysates and Other Biological Fluids
Detection Range
0.312-20ng/mL
Molecular Weight
105,324 Da
OMIM
Y00839 mRNA
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Standard
Recombinant GaA (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685

Product Categories/Family for GaA antibody pair kit

Enzyme & Kinase; Metabolic pathway
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for GaA antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex

Other Notes

Small volumes of GaA antibody pair kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GaA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Glucosidase, alpha; acid
NCBI Official Synonym Full Names
glucosidase alpha, acid
NCBI Official Symbol
GAA
NCBI Official Synonym Symbols
LYAG
UniProt Protein Name
Lysosomal alpha-glucosidase
UniProt Synonym Protein Names
Acid maltase; Aglucosidase alfa
Protein Family
Lysosomal alpha-glucosidase
UniProt Gene Name
GAA
NCBI Protein Information
lysosomal alpha-glucosidase

NCBI Summary for GaA

This gene encodes lysosomal alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. The encoded preproprotein is proteolytically processed to generate multiple intermediate forms and the mature form of the enzyme. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
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UniProt Comments for GaA

Essential for the degradation of glycogen in lysosomes (PubMed:1856189, PubMed:7717400, PubMed:14695532, PubMed:18429042). Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans (PubMed:29061980).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GaA antibody pair kit

 Reference Product  PubMed Publications
 AGA antibody pair kit  >27 publications with GaA and AGA
 GLA antibody pair kit  >8 publications with GaA and GLA
 YY1 antibody pair kit  >2 publications with GaA and YY1
 MGAM antibody pair kit  >1 publications with GaA and MGAM
 AGL antibody pair kit  >1 publications with GaA and AGL

Pathways associated with GaA antibody pair kit

 Products by Pathway  Pathway Diagram
 Galactose Metabolism Pathway antibodies  Galactose Metabolism Pathway Diagram
 Galactose Metabolism Pathway antibodies  Galactose Metabolism Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Notch-mediated HES/HEY Network Pathway antibodies  Notch-mediated HES/HEY Network Pathway Diagram
 Starch And Sucrose Metabolism Pathway antibodies  Starch And Sucrose Metabolism Pathway Diagram
 Starch And Sucrose Metabolism Pathway antibodies  Starch And Sucrose Metabolism Pathway Diagram

Diseases associated with GaA antibody pair kit

 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >738 publications with GaA and Brain Diseases
 Glycogen Storage Disease Type II Antibodies  >342 publications with GaA and Glycogen Storage Disease Type II
 Cardiovascular Diseases Antibodies  >123 publications with GaA and Cardiovascular Diseases
 Cardiomyopathy, Hypertrophic Antibodies  >54 publications with GaA and Cardiomyopathy, Hypertrophic
 Liver Neoplasms Antibodies  >43 publications with GaA and Liver Neoplasms
 Kidney Diseases Antibodies  >42 publications with GaA and Kidney Diseases
 Atrophy Antibodies  >41 publications with GaA and Atrophy
 Hypertrophy Antibodies  >34 publications with GaA and Hypertrophy
 Hypertrophy, Left Ventricular Antibodies  >15 publications with GaA and Hypertrophy, Left Ventricular
 Fibrosis Antibodies  >13 publications with GaA and Fibrosis

Organs/Tissues associated with GaA antibody pair kit

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >348 publications with GaA and Blood
 Muscle Antibodies  >321 publications with GaA and Muscle
 Brain Antibodies  >150 publications with GaA and Brain
 Kidney Antibodies  >62 publications with GaA and Kidney
 Skin Antibodies  >62 publications with GaA and Skin
 Vascular Antibodies  >50 publications with GaA and Vascular
 Pancreas Antibodies  >44 publications with GaA and Pancreas
 Bone Antibodies  >35 publications with GaA and Bone
 Lung Antibodies  >30 publications with GaA and Lung
 Embryonic Tissue Antibodies  >16 publications with GaA and Embryonic Tissue