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Isochenodeoxycholic Acid-D4

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Katalog-Nummer TMIH-0286-25mg

Size : 25mg

Marke : TargetMol


Isochenodeoxycholic Acid-D4

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Isochenodeoxycholic Acid-D4 is a deuterated derivative of Isochenodeoxycholic Acid (T207107), which can be used for isotope-labeled isomeric bile acid metabolism and signaling research. Isochenodeoxycholic Acid can activate farnesoid X receptor (FXR) signaling in cell systems and induce FXR target genes Ostβ and Kng1 in HepG2 cells. Isochenodeoxycholic Acid can also serve as a substrate for recombinant human class I alcohol dehydrogenase γγ-mediated 3β-dehydrogenation, with a catalytic efficiency of 0.09 min−1·μmol/L−1. Isochenodeoxycholic Acid-D4 can support analytical tracer research on bile acid metabolism, FXR-related signaling, and isochenodeoxycholic acid conversion processes.
Isochenodeoxycholic Acid-D4
Other Forms of Isochenodeoxycholic Acid-D4:
Isochenodeoxycholic acidT207107566-24-5
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For research use only—not for human use. No sales to individuals. Use as intended only.

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Appearance:Solid
Color:White

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Bioactivity
Description
Isochenodeoxycholic Acid-D4 is a deuterated derivative of Isochenodeoxycholic Acid (T207107), which can be used for isotope-labeled isomeric bile acid metabolism and signaling research. Isochenodeoxycholic Acid can activate farnesoid X receptor (FXR) signaling in cell systems and induce FXR target genes Ostβ and Kng1 in HepG2 cells. Isochenodeoxycholic Acid can also serve as a substrate for recombinant human class I alcohol dehydrogenase γγ-mediated 3β-dehydrogenation, with a catalytic efficiency of 0.09 min−1·μmol/L−1. Isochenodeoxycholic Acid-D4 can support analytical tracer research on bile acid metabolism, FXR-related signaling, and isochenodeoxycholic acid conversion processes.
Chemical Properties
Molecular Weight396.6
FormulaC24H36D4O4
SmilesOC(CC[C@H]([C@@]1(00)CC[C@@]2(00)[C@]3(00)[C@H](O)C[C@]4(00)C([2H])([2H])[C@@H](O)C([2H])([2H])C[C@]4(C)[C@@]3(00)CC[C@]12C)C)=O
Storage & Solubility Information
StorageStore under nitrogen,Store at low temperature,Keep away from moisture,Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.