KSR1 Recombinant Antibody, Biotin Conjugated
Katalog-Nummer bsm-61694R-Biotin
Size : 100uL
Marke : Bioss
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61694r-biotin |
| Product Name | KSR1 Recombinant Antibody, Biotin Conjugated |
| Applications | WB, IHC-P, IHC-F |
| Reactivity | Human, Mouse |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human KSR1 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 8844 |
| Swiss Prot | Q8IVT5 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | BKSR1; dKsr; EK31; KSR; KSR1; RSU2; SR31. |
| Background | Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases.Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of BRAF; upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2. |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC-P | 1:200-400 |
| IHC-F | 1:100-500 |