L-DABA [1758-80-1]

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Katalog-Nummer T7595-25mg

Size : 25mg

Marke : TargetMol


L-DABA

(Synonyms: L-DAB HBR, L-2,4-Diaminobutyric acid) Copy Product Info
L-DABA (L-2,4-Diaminobutyric acid) is an inhibitor of GABA transaminase with an IC50 greater than 500 μM.
L-DABA
Cas No. 1758-80-1
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.32%
Appearance:Solid
Color:White
COA LCMS HNMR

Product Introduction

Bioactivity
Description
L-DABA (L-2,4-Diaminobutyric acid) is an inhibitor of GABA transaminase with an IC50 greater than 500 μM.
In vitro
L-2,4-Diaminobutyric acid(DABA) was a non-linear, non-competitive inhibitor of GABA transaminase activity. The DABA-induced elevation of GABA levels paralleled the inhibition of GABA transaminase activity. DABA was a more effective inhibitor of GABA transaminase in vivo than in vitro, and this inhibition probably produced the elevation of GABA levels. The neurotoxicity of DABA appears to produce a use in GABA replacement therapy[1].
SynonymsL-DAB HBR, L-2,4-Diaminobutyric acid
Chemical Properties
Molecular Weight118.13
FormulaC4H10N2O2
Cas No.1758-80-1
SmilesNCC[C@H](N)C(O)=O
Relative Density.1.218 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: Insoluble
H2O: Insoluble