Latrophilin 1 antibody
Katalog-Nummer GTX71123-25ug
Size : 25ug
Marke : Genetex
Host | Rabbit |
---|---|
Clonality | Polyclonal |
Isotype | IgG |
Application | IHC-P |
Reactivity | Human, Mouse, Rat, Rabbit, Bovine, Dog, Hamster, Pig, Monkey, Bat |
Package | 25 μg |
View product citations for antibody GTX71123 on CiteAb
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application | Recommended Dilution |
---|---|
IHC-P | 8 μg/ml |
Not tested in other applications.
Calculated MW
163 kDa. ( Note )
Predict Reactivity
Elephant, Gibbon, Gorilla, Lizard, Marmoset, Opossum, Panda, Xenopus, Platypus(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.74 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 16 amino acid peptide from N-terminal extracellular domain of human LPHN1.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_375567
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
adhesion G protein-coupled receptor L1 , ADGRL1 , CIRL1 , CL1 , LEC2 , LPHN1 , adhesion G proteincoupled receptor L1 , Latrophilin-1
Cellular Localization
Cell membrane,Cell projection,Axon,Growth cone,Cell junction,Synapse,Presynaptic cell membrane,Synaptosome
Background
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]
Database
DATA IMAGES
GTX71123 IHC-P Image IHC-P analysis of human brain, neurons and glia tissue using GTX71123 Latrophilin 1 antibody. |
REVIEW
SDS | |
---|---|
PBS.pdf | |
Sodium Azide.pdf |