350528 | MSH2 Peptide Clinisciences

Blocking Peptide

Synthetic Peptide

Cat. No.

350528

Unit

0.1 mg

Description

DNA mismatch repair protein Msh2 (MSH2) is a component of the post-replicative DNA mismatch repair system (MMR). MSH2 forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) that bind to DNA mismatches and initiate DNA repair. Defects in MSH2 are the cause of hereditary non-polyposis colorectal cancer type 1 and endometrial cancers.

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Datasheet

Format

Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

Alternate Names

DNA mismatch repair protein Msh2; MutS protein homolog 2; MSH2

Accession No.

P43246

2001.4 g/mol

Sequence

The synthetic peptide used to raise the antibody Cat. No. 200166 is selected from a sequence within the C-term region of human MSH2. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Composition

C87H157N25O26S1

Purity

Purity > 80% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.

Related Products

Antibody Products
Product Name	Applications	SKU
MSH2 (1B3) Antibody	WB, IHC, IF	252617
MSH2 Antibody	E, IHC, WB	200166
Msh2 Antibody	E, WB, IHC, IP	251270

Lysate Products
Product Name	Applications	SKU
MSH2 293 Cell Lysate	ELISA, WB, IP	410290

For research use only, not for diagnostic or therapeutic procedures.

MSH2 Peptide

Katalog-Nummer 350528

Marke : Abbiotec

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