PE Anti-Mouse CD51 Antibody[RMV-7]
Katalog-Nummer E-AB-F1235D-200
Size : 100Testsx2
Marke : Elabscience
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Cell Markers ![PE Anti-Mouse CD51 Antibody[RMV-7] - 1](/proxy_img/Ly9maWxlLmVsYWJzY2llbmNlLmNvbS9hc3NldHMvaW1hZ2VzL2xvYWRpbmcucG5n.png)
For research use only.
Conjugation: PE
APC Biotin PE PE/Cyanine 7 Unconjugated Show More
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| Alternate Names | ITGAV, Integrin alpha-V, Integrin αV chain, Vitronectin Receptor, αV integrin |
| Clone | |
| Leadtime | Order now, ship in 3 days |
| Background | CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αvintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity. |
| Abbre | CD51 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Isotype | Rat IgG1, κ |
| Isotype Control | PE Rat IgG1, κ Isotype Control[HRPN] |
| Applications | FCM |
| Research Areas | Angiogenesis;Cell Adhesion;Cell Biology;Costimulatory Molecules;Immunology;Innate Immunity;Stem Cells |
| Cellular Localization | Membrane |
| Form | Liquid |
| Concentration | 5 μL/Test |
| Conjugation | PE |
| Conjugation Information | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 24 months |
| Shipping | Ice bag |
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