Reagenzien und Instrumente für die Immunologie Zellbiologie und Molekularbiologie
 
> PLGA (50:50) [34346-01-5]

PLGA (50:50) [34346-01-5]

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Katalog-Nummer HY-B2247-500mg

Size : 500mg

Marke : MedChemExpress


Beschreibung

PLGA (50:50) (poly(lactic-co-glycolic acid) (50:50)) is a copolymer of poly lactic acid (PLA) and poly glycolic acid (PGA) which can be used to fabricate devices for drug delivery and tissue engineering applications.

In Vitro

PLGA (50:50) can be used to prepare nanoparticles with different surface properties for biological experiments[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

PLGA (50:50) Related Antibodies

Lösungsmittel & Löslichkeit
In Vitro: 

DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 2.5 mg/mL; Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.
Reinheit & Dokumentation
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