Recombinant Human Follicle-Stimulating Hormone alpha/beta Dimer Protein

Katalog-Nummer MBS2552685-0,05mg

Size : 0.05mg

Marke : MyBiosource


Follicle-Stimulating Hormone Alpha/Beta Dimer (CGA) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2552685

Human Follicle-stimulating hormone (FSH) is a member of glycoprotein hormones subunit beta family, whichalso includes LH, chorionic gonadotropin (CG) and thyroid-stimulating hormone (TSH). FSH and its familymembers are heterodimers consisting of… More details

Product Overview

Online Datasheet in PDF
Product Name
Follicle-Stimulating Hormone alpha/beta Dimer (CGA), Recombinant Protein
Full Product Name
Recombinant Human Follicle-Stimulating Hormone alpha/beta Dimer Protein
Product Gene Name
CGA recombinant protein
Product Synonym Names
Follicle-stimulating hormone; FSH; FSH alpha/beta
Host
Human Cells
Form/Format
Lyophilized from a 0.2 mum filtered solution of PBS, pH 7.4.
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Preparation and Storage
Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Molecular Weight
Molecular Mass: 10.2; 12.5 kDa
Actual Protein Molecular Mass: 20 kDa
Sequence Positions
Ala25-Ser116 & Asn19-Glu129
3D Structure
ModBase 3D Structure for P01215
Species
Human
Endotoxin
<1.0 EU per ug as determined by LAL test.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CGA recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CGA purchase

MBS2552685 is a recombinant protein targeting CGA. Also known as Recombinant Human Follicle-Stimulating Hormone alpha/beta Dimer Protein. Host: Human Cells.

Additional Details

NCBI/Uniprot data below describe general gene information for CGA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
glycoprotein hormones alpha chain isoform 2
NCBI Official Synonym Full Names
glycoprotein hormones, alpha polypeptide
NCBI Official Symbol
CGA
NCBI Official Synonym Symbols
HCG; LHA; FSHA; GPHa; TSHA; GPHA1; CG-ALPHA
UniProt Protein Name
Glycoprotein hormones alpha chain
UniProt Synonym Protein Names
Anterior pituitary glycoprotein hormones common subunit alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; CG-alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; Luteinizing hormone alpha chain; LSH-alpha; Lutropin alpha chain; Thyroid-stimulating hormone alpha chain; TSH-alpha; Thyrotropin alpha chain
Protein Family
Glycoprotein hormones
UniProt Gene Name
CGA
UniProt Synonym Gene Names
CG-alpha; FSH-alpha; LSH-alpha; TSH-alpha
NCBI Protein Information
glycoprotein hormones alpha chain

NCBI Summary for CGA

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
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UniProt Comments for CGA

Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CGA recombinant protein

 Reference Product  PubMed Publications
 LHB recombinant protein  >28 publications with CGA and LHB
 FSHB recombinant protein  >27 publications with CGA and FSHB
 FSHR recombinant protein  >6 publications with CGA and FSHR
 TSHB recombinant protein  >5 publications with CGA and TSHB
 LHCGR recombinant protein  >3 publications with CGA and LHCGR
 CGB8 recombinant protein  >1 publications with CGA and CGB8

Pathways associated with CGA recombinant protein

 Products by Pathway  Pathway Diagram
 Amine-derived Hormones Pathway antibodies  Amine-derived Hormones Pathway Diagram
 Androgen Biosynthesis Pathway antibodies  Androgen Biosynthesis Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 FSH Signaling Pathway antibodies  FSH Signaling Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram

Diseases associated with CGA recombinant protein

 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >280 publications with CGA and Adenocarcinoma
 Nervous System Diseases Antibodies  >170 publications with CGA and Nervous System Diseases
 Prostatic Neoplasms Antibodies  >137 publications with CGA and Prostatic Neoplasms
 Lung Neoplasms Antibodies  >116 publications with CGA and Lung Neoplasms
 Cardiovascular Diseases Antibodies  >108 publications with CGA and Cardiovascular Diseases
 Disease Progression Antibodies  >95 publications with CGA and Disease Progression
 Hyperplasia Antibodies  >77 publications with CGA and Hyperplasia
 Liver Diseases Antibodies  >68 publications with CGA and Liver Diseases
 Liver Neoplasms Antibodies  >68 publications with CGA and Liver Neoplasms
 Neoplasm Metastasis Antibodies  >67 publications with CGA and Neoplasm Metastasis

Organs/Tissues associated with CGA recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >168 publications with CGA and Brain
 Lung Antibodies  >165 publications with CGA and Lung
 Liver Antibodies  >138 publications with CGA and Liver
 Stomach Antibodies  >137 publications with CGA and Stomach
 Thyroid Antibodies  >105 publications with CGA and Thyroid
 Heart Antibodies  >102 publications with CGA and Heart
 Vascular Antibodies  >100 publications with CGA and Vascular
 Muscle Antibodies  >99 publications with CGA and Muscle
 Pituitary Gland Antibodies  >73 publications with CGA and Pituitary Gland
 Skin Antibodies  >58 publications with CGA and Skin