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> TEAD4 Protein, Human, Recombinant (His & Myc)

TEAD4 Protein, Human, Recombinant (His & Myc)

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Katalog-Nummer NB-64-50895-1mg

Size : 1mg

Marke : Neo Biotech


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TEAD4 Protein, Human, Recombinant (His & Myc)

(Synonyms: Transcriptional enhancer factor TEF-3, Transcription factor RTEF-1, Transcription factor 13-like 1, TEF3, TEAD4, TEA domain family member 4 (TEAD-4), TCF13L1, RTEF1) Copy Product Info

Synonyms: Transcriptional enhancer factor TEF-3, Transcription factor RTEF-1, Transcription factor 13-like 1, TEF3, TEAD4, TEA domain family member 4 (TEAD-4), TCF13L1, RTEF1

Catalog No. TMPH-02224 Copy Product Info
TEAD4 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 44.5 kDa and the accession number is Q15561.
Other Forms of TEAD4 Protein, Human, Recombinant (His & Myc):
TEAD4 Protein, Human, Recombinant (His)
TEAD4 Protein, Mouse, Recombinant (His & Myc)
TEAD4 Protein, Mouse, Recombinant
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Information

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
TEAD4 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 44.5 kDa and the accession number is Q15561.
Species
Human
Expression System
Baculovirus Insect Cells
TagN-10xHis, C-Myc
Accession NumberQ15561
Amino AcidMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKAREIQAKLKDQAAKDKALQSMAAMSSAQIISATAFHSSMALARGPGRPAVSGFWQGALPGQAGTSHDVKPFSQQTYAVQPPLPLPGFESPAGPAPSPSAPPAPPWQGRSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGQSSPSYSDPYLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFLVKFWADLNTNIEDEGSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE
Construction74-434 aa
Protein Purity
> 85% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
ReconstitutionReconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsTranscriptional enhancer factor TEF-3, Transcription factor RTEF-1, Transcription factor 13-like 1, TEF3, TEAD4, TEA domain family member 4 (TEAD-4), TCF13L1, RTEF1
Research Background
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif.
Chemical Properties
Molecular Weight44.5 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

TEF 3TEAD-4TEAD 4TCF13L 1RTEF 1
Related Tags: TEAD4 Protein, Human, Recombinant (His & Myc) chemical structure | TEAD4 Protein, Human, Recombinant (His & Myc) molecular weight